Gestational diabetes mellitus is associated with distinct folate‐related metabolites in early and mid‐pregnancy: A prospective cohort study
Wei Zheng,
Yujie Zhang,
Puyang Zhang
et al.
Abstract:AimsThis study aimed to evaluate the association between gestational diabetes mellitus (GDM) and circulating folate metabolites, folic acid (FA) intake, and the methylenetetrahydrofolate reductase (MTHFR) and methionine synthase reductase (MTRR) genotype.Materials and MethodsA prospective pregnancy cohort study was conducted in Beijing, China, from 2022 to 2023. Circulating folate metabolites, including red blood cell (RBC) 5‐methyltetrahydrofolate (5‐MTHF), 5, 10‐methylene‐tetrahydrofolate (5,10‐CH2‐THF), 5‐ … Show more
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