Gestational diabetes and the neonate: challenges and solutions

Stewart, Alice; Malhotra, Atul

doi:10.2147/rrn.s30971

Cited by 9 publications

(2 citation statements)

References 72 publications

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“…A higher prevalence of GDM was observed in mothers with a family history of T2DM 18 23 24. Further, a study on Russian women also identified that a genetic variant in MTNR1B is associated with an increased risk of GDM 25.…”

Section: Introductionmentioning

confidence: 93%

Incidence and risk factors of gestational diabetes mellitus in Goba town, Southeast Ethiopia: a prospective cohort study

et al. 2022

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ObjectiveGestational diabetes mellitus (GDM) is becoming a public health concern in low/middle-income countries, and is known to cause severe morbidity and mortality for mothers and newborns. However, evidence reported for the incidence and risk factors of GDM is scant in Ethiopia. We aimed to assess the incidence of, and risk factors for, GDM in Goba town, Southeast Ethiopia.DesignProspective cohort study.SettingGoba town, Southeast Ethiopia.ParticipantsFour hundred eighty pregnant women on antenatal care follow-up from 30 April to 30 September 2021.Primary and secondary outcomesIncidence and risk factors of GDM using fasting capillary blood glucose. Log-binomial model was used to identify the risk factors of GDM. Adjusted relative risk (aRR), along with 95% CIs, were calculated to estimate the strength of associations.ResultsThe cumulative incidence rate of GDM in this study was 15.7% (95% CI: 12.3% to 19.2%). Being unemployed (aRR=2.73; 95% CI: 1.36 to 5.47), having a family history of diabetes mellitus (DM) (3.01; 2.09 to 4.35), low physical activity (2.43; 1.11 to 5.32), inadequate dietary diversity (1.48; 1.29 to 1.92), anaemia (2.51; 1.32 to 3.54) and antenatal depression (4.95; 3.35 to 7.31) were significantly associated with GDM.ConclusionThe cumulative incidence of GDM was relatively high among the study participants. Having antenatal depression symptoms, low physical activity, inadequate dietary diversity, being unemployed, anaemia and a family history of DM were significant risk factors for GDM.

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Section: Introductionmentioning

confidence: 93%

Incidence and risk factors of gestational diabetes mellitus in Goba town, Southeast Ethiopia: a prospective cohort study

et al. 2022

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“…Randomized controlled trials demonstrate that the treatment of gestational diabetes reduces macrosomia, which is a significant risk factor for perinatal complications [7,8]. Besides optimal obstetric management, communication between obstetrics and neonatology is critical to plan for possible neonatal resuscitation, assessment, and care of IDMs [9].…”

Section: Introductionmentioning

confidence: 99%

Optimally Controlled Diabetes and Its Influence on Neonatal Outcomes at a Level II Center: A Study on Infants Born to Diabetic Mothers

Muntean,

Prelipcean,

Racean

et al. 2023

Medicina

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Background and Objectives: We investigated the effect of optimal maternal glycemic control on neonatal outcomes among infants born to mothers with diabetes. Materials and Methods: In this prospective study, we assessed 88 eligible mothers admitted to the obstetrics department for pregnancy evaluation. Our analysis included 46 infants born to diabetic mothers (IDMs) and 138 infants born to unaffected mothers, all admitted to the Level II Neonatal Intensive Care Unit (NICU). Results: Mothers affected by diabetes were generally older and exhibited a higher body mass index (BMI) and a greater number of gestations, although parity did not differ significantly. Cesarean section emerged as the most frequently chosen mode of delivery. A significantly higher proportion of infants in the affected group presented with respiratory disease (3% vs. 19.5%), which required NICU admission (4.3% vs. 23.9%), phototherapy (18.1% vs. 43.5%), and had congenital heart defects or myocardial hypertrophy (15.2% and 26% vs. 3% and 4.3%) compared to matched controls (p < 0.05). Conclusions: This study underscores the persistence of adverse neonatal outcomes in IDMs, even when maternal glycemic control is optimized. It calls for further investigation into potential interventions and strategies aimed at enhancing neonatal outcomes in this population.

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Impact of Maternal Health and Disease on Neonatal Outcome

Kathuria¹

2023

Clinical Anesthesia for the Newborn and the Neonate

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Gestational diabetes and the neonate: challenges and solutions

Cited by 9 publications

References 72 publications

Incidence and risk factors of gestational diabetes mellitus in Goba town, Southeast Ethiopia: a prospective cohort study

Incidence and risk factors of gestational diabetes mellitus in Goba town, Southeast Ethiopia: a prospective cohort study

Optimally Controlled Diabetes and Its Influence on Neonatal Outcomes at a Level II Center: A Study on Infants Born to Diabetic Mothers

Impact of Maternal Health and Disease on Neonatal Outcome

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