Gestational breast cancer: current challenges in staging and treatment of breast cancer

Abstract

Gestational breast cancer (GBC) is the most common form of invasive cancer in pregnancy and has unique challenges in both staging and treatment given the dual goal of appropriate cancer management and minimising the risk of fetal toxicity. A 38-year-old woman with no significant medical history and 21 weeks pregnant presented with a palpable right breast mass. She was diagnosed with human epidermal growth factor receptor 2-positive infiltrating ductal carcinoma with advanced disease. The patient underwent treatment; however, unfortunately, she passed away after developing devastating distant disease recurrence.We highlight both the challenges and current guidelines for management of GBC. Our goal is to discuss the current limitations of GBC management and the necessity of further investigation for safe novel imaging and treatment modalities for pregnant women. It is crucial to increase awareness across multiple subspecialities, as a multidisciplinary team is necessary for proper treatment of GBC.

Gestational breast cancer in a patient with Crohn’s disease: two case reports

“…The same approach was followed by Schad et al . and Nye et al ., suggesting the safety and efficiency of this therapeutic plan [ 9 , 10 ].…”

Breast cancer and pregnancy: Why special considerations prior to treatment are needed in multidisciplinary care

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