GESAP trial rationale and methodology: management of patients with suspected obstructive sleep apnea in primary care units compared to sleep units

Tarraubella, Nuria; Batlle, Jordi de; Nadal, Núria; Castro-Grattoni, Anabel L.; Gómez, Sílvia; Sánchez‐de‐la‐Torre, Manuel; Barbé, Ferrán

doi:10.1038/s41533-016-0010-x

Cited by 4 publications

(2 citation statements)

References 23 publications

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“…Recently, two Spanish studies, PASHOS and GESAP, studied a program of the PHC system and a sleep unit for OSAS management. Although the protocol that both studies followed was similar to ours, PSG was not used as the standard test for OSAS diagnosis, and the upper age range was much larger in both studies than in our study [ 36 , 37 ].…”

Section: Discussionmentioning

confidence: 97%

Obstructive Sleep Apnea Syndrome Comorbidity Phenotypes in Primary Health Care Patients in Northern Greece

et al. 2022

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Background: Obstructive sleep apnea syndrome (OSAS) is a significant public health issue. In the general population, the prevalence varies from 10% to 50%. We aimed to phenotype comorbidities in OSAS patients referred to the primary health care (PHC) system. Methods: We enrolled 1496 patients referred to the PHC system for any respiratory- or sleep-related issue from November 2015 to September 2017. Some patients underwent polysomnography (PSG) evaluation in order to establish OSAS diagnosis. The final study population comprised 136 patients, and the Charlson comorbidity index was assessed. Categorical principal component analysis and TwoStep clustering was used to identify distinct clusters in the study population. Results: The analysis revealed three clusters: the first with moderate OSAS, obesity and a high ESS score without significant comorbidities; the second with severe OSAS, severe obesity with comorbidities and the highest ESS score; and the third with severe OSAS and obesity without comorbidities but with a high ESS score. The clusters differed in age (p < 0.005), apnea–hypopnea index, oxygen desaturation index, arousal index and respiratory and desaturation arousal index (p < 0.001). Conclusions: Predictive comorbidity models may aid the early diagnosis of patients at risk in the context of PHC and pave the way for personalized treatment.

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Section: Discussionmentioning

confidence: 97%

Obstructive Sleep Apnea Syndrome Comorbidity Phenotypes in Primary Health Care Patients in Northern Greece

et al. 2022

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“…The methodology of the study has been published previously 14. In this multicentre, open-label, two-arm, parallel-group, prospective, non-inferiority randomised controlled trial, patients were consecutively recruited from 11 PC units during visits for suspected OSA (chronic snoring, apnoea and/or excessive daytime sleepiness (EDS)) or resistant hypertension (defined as blood pressure (BP) higher than the therapeutic goals (ie, average systolic BP ≥130 mm Hg, average diastolic BP ≥80 mm Hg or both) despite the concurrent use of at least three antihypertensive agents prescribed at doses that provide optimal benefit, with one of these drugs ideally being a diuretic agent 15.…”

Section: Methodsmentioning

confidence: 99%

Management of obstructive sleep apnoea in a primary care vs sleep unit setting: a randomised controlled trial

Tarraubella

Sánchez‐de‐la‐Torre

Nadal

et al. 2018

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Upcoming Scenarios for the Comprehensive Management of Obstructive Sleep Apnea: An Overview of the Spanish Sleep Network

Mediano

Cano‐Pumarega

Sánchez‐de‐la‐Torre

et al. 2020

Archivos de Bronconeumología (English Edition)

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GESAP trial rationale and methodology: management of patients with suspected obstructive sleep apnea in primary care units compared to sleep units

Cited by 4 publications

References 23 publications

Obstructive Sleep Apnea Syndrome Comorbidity Phenotypes in Primary Health Care Patients in Northern Greece

Obstructive Sleep Apnea Syndrome Comorbidity Phenotypes in Primary Health Care Patients in Northern Greece

Management of obstructive sleep apnoea in a primary care vs sleep unit setting: a randomised controlled trial

Upcoming Scenarios for the Comprehensive Management of Obstructive Sleep Apnea: An Overview of the Spanish Sleep Network

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