Germline genetic variants in Turkish familial multiple myeloma/monoclonal gammopathy of undetermined significance cases
Erman Akkus,
Timur Tuncalı,
Hasan Yalım Akın
et al.
Abstract:SummaryMultiple myeloma (MM) is a haematological malignancy primarily affecting the elderly, with a striking male predilection and ethnic disparities in incidence. Familial predisposition to MM has long been recognized, but the genetic underpinnings remain elusive. This study aimed to investigate germline variants in Turkish families with recurrent MM cases. A total of 37 MM‐affected families, comprising 77 individuals, were included. Targeted next‐generation sequencing analysis yielded no previously reported … Show more
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