Germ cell tumours in uncorrected cryptorchid testis at Institute Rotary Cancer Hospital, New Delhi

Raina, Vinod; Shukla, N.K.; Gupta, Nidhi; Deo, S. V. S.; Rath, GK

doi:10.1038/bjc.1995.77

Cited by 24 publications

(6 citation statements)

References 19 publications

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“…Gauwitz et al (10) confirms this observation and reports a 33% (3 of 9) incidence in SUIC, not significantly different from the 25% incidence observed in scrotal seminoma, but significantly lower than in patients with pelvic cryptorchid seminoma (76%, 13 of 17 ) . These data, however, are in contrast with most other published reports on nodal metastases in cryptorchid seminoma ( 1,2,20,32). However, the latter reports contain a smaller number of patients as compared with the former.…”

Section: Lymphatic Metastasescontrasting

confidence: 68%

“…In contrast to patients with scrotal seminoma, clinical studies report a high proportion of advanced stage disease in patients with cryptorchid seminoma. The optimal management after orchiectomy for cryptorchid seminoma is less well established and the prognosis is controversial ( 1,2,10,18,20,32). It remains unclear whether the poor prognosis observed in inguinal seminoma is due to advanced stage or other factors.…”

Section: Introductionmentioning

confidence: 99%

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Seminoma arising in corrected and uncorrected inguinal cryptorchidism: Treatment and prognosis in 66 patients

Coucke

Qian

et al. 1997

International Journal of Radiation Oncology*Biology*Physics

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Purpose: The purpose of this study was to analyze prognosis and treatment results for seminoma arising in corrected and uncorrected inguinal cryptorchidism (SCIC and SUIC). Methods and Materials: We reviewed 66 patients with inguinal seminomas between June 1958 and December 1991 at the Cancer Hospital and Institute of Chinese Academy of Medical Sciences. Of these patients, 23 had prior orchiopexy and 43 presented with an inguinal form of cryptorchidism. At presentation, 17 of 66 (26%) patients had nodal metastases. This nodal involvement was 30% (7 of 23) for SCIC and 23% (10 of 43) for SUIC, respectively. These numbers are comparable with those in a series of patients treated for scrotal seminoma at our institution (26% vs. 20%). However, 3 of 23 (13%) patients who had prior orchiopexy presented with inguinal nodal metastasis as compared with 0 of 43 patients with SUIC or 4 of 237 patients with scrotal seminoma (p < .05). There were 49 stage I, 5 stage IIA, 8 stage IIB, 3 stage III, and 1 stage IV patients. All patients underwent radical orchiectomy and received further radiotherapy, chemotherapy, or both. Patients with stage I and stage II disease were treated primarily with radiotherapy, whereas patients with stage III and IV disease were treated with chemotherapy. Results: The overall and disease-free survival at 5 and 10 years was 94% and 92%, 89% and 87%, respectively. The overall 5-and lo-year survival by stage was 100% and 100% for stage I, and 77% and 68% for stage II, respectively @ < .05). There was no significant difference in survival between SUIC and SCIC (93% vs. 96% at 5 years). Four patients developed relapse. Two of these four patients experienced relapse at the inguinal area, due to a marginal miss. Three of four patients with relapse were successfully salvaged, and one died of disease. Conclusion: Our results indicate that prognosis for inguinal seminoma is excellent and similar to that of scrotal seminoma. Postorchiectomy radiotherapy can be considered as the standard treatment for stage I and IIA inguinal seminoma. We recommend routinely including the para-aortic and ipsilateral pelvic nodes. 0 1997 Elsevier Science Inc. Seminoma, Cryptorchidism, Radiotherapy.

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Section: Lymphatic Metastasescontrasting

confidence: 68%

Section: Introductionmentioning

confidence: 99%

Seminoma arising in corrected and uncorrected inguinal cryptorchidism: Treatment and prognosis in 66 patients

Coucke

Qian

et al. 1997

International Journal of Radiation Oncology*Biology*Physics

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“…Undescended testis is rarely seen in adults in the Western world. In India, however, 14% of adult patients with germ cell tumors of testis have undescended testis [16]. In a unique study, Raghavendran et al analyzed the late presentation of Indian patients with undescended testis.…”

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confidence: 96%

Laparoscopic orchiectomy for the adult impalpable testis – experiences in a rural teaching hospital

Rangarajan

Jayakar

2006

Surg Endosc

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“…We did not find any cases of testicular malignancy or any other abnormality in the specimens during the histopathology examinations 2 ; however, one study from India reported that almost 14% of testicular tumours were found to be in the cryptorchid testis. 26…”

Section: Discussionmentioning

confidence: 99%

Is laparoscospic orchidectomy the treatment of choice in adults with impalpable testis in rural hospitals in the developing world?

Mir¹,

Mohsin²,

Kirmani³

et al. 2009

Trop Doct

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This study was undertaken in order to evaluate the feasibility and safety of performing laparoscopic orchidectomy (LO) in men for unilateral impalpable testis in non-teaching rural hospitals in a developing country. We also investigated the possibility of reducing the cost and length of stay in hospital for patients undergoing LO. This is a prospective analysis of patients with impalpable testis undergoing LO in three non-teaching rural hospitals in the Kashmir Valley from January 2001 to March 2007. The cohort represented men requiring LO aged 15 to 62 (mean 36.2) years. The main outcome parameters assessed included mortality, conversion to an open procedure, complications, reduction in the costs and the length of the hospital stay. Forty-eight men with unilateral undescended testis on physical examination were studied. During laparoscopy the testis was identified near the deep ring in 30 patients, intra-abdominally in 16, and two had blind-ending vas and spermatic vessels near the deep ring. In 46 patients orchidectomy was performed. There were no deaths and none of the patients required conversion to an open procedure. Using reusable instruments, 00 degrees polyglactin sutures and self-made extraction bags, about US$ 300/patient was saved. There was no case of malignancy of the testis on histopathology examination. LO is one of the most satisfactory methods for the management of men with impalpable testis, having both a diagnostic and a therapeutic role especially for patients in the underdeveloped countries. These simple methods can reduce the cost and the length of the hospital stay.

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Germ cell tumours in uncorrected cryptorchid testis at Institute Rotary Cancer Hospital, New Delhi

Cited by 24 publications

References 19 publications

Seminoma arising in corrected and uncorrected inguinal cryptorchidism: Treatment and prognosis in 66 patients

Seminoma arising in corrected and uncorrected inguinal cryptorchidism: Treatment and prognosis in 66 patients

Laparoscopic orchiectomy for the adult impalpable testis – experiences in a rural teaching hospital

Is laparoscospic orchidectomy the treatment of choice in adults with impalpable testis in rural hospitals in the developing world?

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