Germ Cell Tumors/Teratoma

Frazier, A. Lindsay; Brodsky, Jacob R.; Kanwar, Vikramjit S.; Stafford, Lisa M.; Rahbar, Reza

doi:10.1007/978-1-4614-8755-5_20

Cited by 1 publication

(1 citation statement)

References 72 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…There is controversy on the diagnostic value of serum alpha-fetoprotein for mature teratomas [19], especially in the newborn period, being normally high as a result of fetal production [20]. However, elevated serum alpha-fetoprotein levels may signal the presence of regional recurrence or metastatic disease in the setting of malignant teratoma [21]. The levels in our patient were elevated preoperatively and returned back to normal postoperatively, with no recurrence of the tumor.…”

Section: Discussionmentioning

confidence: 78%

Congenital Orbital Teratoma

Pellerano

Guillermo²,

Garrido³

et al. 2016

Ocul Oncol Pathol

View full text Add to dashboard Cite

We report a case of congenital orbital teratoma. A 3-day-old male, born at 39 weeks' gestation without relevant prenatal history, presented with a large vascularized proptotic mass distorting the left midface. Laboratory studies showed elevated serum alpha-fetoprotein (12,910 ng/ml). Computed tomography showed a multiloculated heterogeneous lesion composed of hypodense and hyperdense calcified areas encompassing the whole orbital cavity with expansion of the bony walls, as well as forward displacement and compression of the eyeball without extension to surrounding structures. Clinical, imaging and laboratory features were consistent with congenital orbital teratoma. Due to pronounced proptosis with exposure keratopathy and corneal perforation, no motility of the globe and no vision in the affected eye in a resource-limited setting, the patient underwent orbital exenteration. Histopathological examination confirmed the diagnosis of mature cystic teratoma. We describe the clinical course, radiographic and histopathological findings of this rare orbital tumor.

show abstract

Section: Discussionmentioning

confidence: 78%