Gerinnungsphysiologische und Plasmaeiwei�untersuchungen bei normalen (Menses) und pathologischen uterinen Blutungen

Beller, F. K.; H, Graf

doi:10.1007/bf00989611

Cited by 16 publications

(3 citation statements)

References 68 publications

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“…In the present work, cyclic variation during the menstrual cycle in the parameters studied was found only with respect to the number of platelets. Such changes have been reported previously by others (Dameshek 1932, Gene11 1936, Pohle 1939, Kelly et al 1953, Pepper & Lindsay 1956, Beller & Graf 1957. As for cyclic variation of other parameters in blood coagulation and fibrinolysis, varying results are found in the literature, probably because of different methods used.…”

Section: Discussionsupporting

confidence: 56%

Variation in the Individual Subject of Some Parameters in Blood Coagulation and Fibrinolysis

Ygge

1969

Scandinavian Journal of Haematology

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Five young, healthy women with regular menstruations and who were not taking oral contraceptives were followed with repeated blood samples for 5 weeks. On each individual, about 15 determinations were made of the number of platelets, the fibrinogen and plasminogen concentration, the P & P‐test, the Factor VIII activity and the spontaneous fibrinolytic activity of the euglobulin fraction of plasma on fibrin plates. It was shown that the variation in these parameters in the individual was smaller than the variation between individuals and that distinct individual ranges could be found for some women. This was most pronounced with respect to the number of platelets, the fibrinogen concentration and the P&P‐test. The importance of knowing normal intra‐individual ranges of different parameters in blood coagulation and fibrinolysis is stressed. Cyclic variations in the number of platelets were found during the menstrual cycle but there were no such variations in the other parameters studied.

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Section: Discussionsupporting

confidence: 56%

Variation in the Individual Subject of Some Parameters in Blood Coagulation and Fibrinolysis

Ygge

1969

Scandinavian Journal of Haematology

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“…The amount of menstrual blood loss is influenced, among other factors, by the efficiency of the hemostatic mechanism. The human endometrium contains both thromboplastic and fibrinolytic components (3,4,8,12,18,29,31). Most authors (4,12,22,30,35) are of the opinion that clotting of the blood entering the uterine cavity is followed by fibrinolysis.…”

mentioning

confidence: 99%

“…Most authors (4,12,22,30,35) are of the opinion that clotting of the blood entering the uterine cavity is followed by fibrinolysis. Beller et al (6,7,8) on the other hand claim that there is only lysis of fibrinogen, i.e. the formation of fibrin does not occur.…”

mentioning

confidence: 99%

Fibrinogen‐Fibrin Degradation Products in Menstrual Blood from Women with Normal and Excessive Menstrual Blood Losses

Hahn

Rybo

1975

Acta Obstet Gynecol Scand

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Fibrinogen-fibrin degradation products, FDP, in menstrual blood during the first three days of menstrual blood during the first three days of menstruation have been investigated. Two groups of women were studied, those with normal menstrual blood loss (15 women, mean loss 30 ml, range 8-60 ml) and those with menorrhagia (14 women, mean loss 222 ml, range 107-729 ml). The following results were obtained: 1). The FDP concentrations decreased during menstruation in both groups. 2). The FDP concentrations in the two were compared for each day of the menstrual period. No differences were found between the two groups. A possible explanation of the results is given: there is a higher rate of coagulation and fibrinolysis in the endometrium of women with menorrhagia compared with women with normal blood losses. The hypothesis is supported by results of studies in which tranexamic is supported by results of studies in which tranexamic acid, an inhibitor of fibrinolysis, was given to reduce the menstrual blood loss. 3). The FDP excretion patterns differed from women to women. There were no consistent differences between the menorrhagic and the control group.

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Synthetic Inhibitors of Fibrinolysis

Markwardt¹

1978

Fibrinolytics and Antifibrinolytics

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Gerinnungsphysiologische und Plasmaeiwei�untersuchungen bei normalen (Menses) und pathologischen uterinen Blutungen

Cited by 16 publications

References 68 publications

Variation in the Individual Subject of Some Parameters in Blood Coagulation and Fibrinolysis

Variation in the Individual Subject of Some Parameters in Blood Coagulation and Fibrinolysis

Fibrinogen‐Fibrin Degradation Products in Menstrual Blood from Women with Normal and Excessive Menstrual Blood Losses

Synthetic Inhibitors of Fibrinolysis

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