“…1 Also 1,4-naphthoquinone is a raw material for various pharmaceutical and agrochemical industries. Its derivatives exhibit biological responses such as antiallergic, 2 antithrombotic, 3 antiviral 4 apoptosis, 5 lipoxygenase inhibitors, 6,7 anti-ringworm 8 and also human DNA topoisomerase I and II inhibitors. 9 The two carbonyl groups present in 1,4-naphthoquinone behave as crucial chromophore that accounts for its bioactivities owing to their ability to accept electrons.…”
Novel 3,4-dihydro-2H-naphtho[2,3-e][1,3]oxazine-5,10-diones have been synthesized via one pot condensation of 2-hydroxy-1,4-naphthoquinone, aromatic amine and formaldehyde in [bmim]BF4.
“…1 Also 1,4-naphthoquinone is a raw material for various pharmaceutical and agrochemical industries. Its derivatives exhibit biological responses such as antiallergic, 2 antithrombotic, 3 antiviral 4 apoptosis, 5 lipoxygenase inhibitors, 6,7 anti-ringworm 8 and also human DNA topoisomerase I and II inhibitors. 9 The two carbonyl groups present in 1,4-naphthoquinone behave as crucial chromophore that accounts for its bioactivities owing to their ability to accept electrons.…”
Novel 3,4-dihydro-2H-naphtho[2,3-e][1,3]oxazine-5,10-diones have been synthesized via one pot condensation of 2-hydroxy-1,4-naphthoquinone, aromatic amine and formaldehyde in [bmim]BF4.
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