Global environmental degradation and climate change causing persistent health issues due to increased exposure to pollution have become a serious matter of concern and studies. This human-generated environmental pollution is caused due to rapid industrialization, construction-related issues, different festive occasions, etc. Remarkable seasonal and spatial distributions have been observed in this context. Among all the existing pollutants, the fine airborne particles P M2.5(with aerodynamic equivalent diameter ≤ 2.5μm) and P M10 (with aerodynamic equivalent diameter ≤ 10μm) are associated with chronic pulmonary and cardiovascular diseases. This leads to carrying out the study regarding the varying relationship between P M2.5 and other related risk factors so that its concentration level might be under control. Existing literature has explored the geographical association between the pollutants with a few other important factors. To address this problem, the present study aims to explore the widespatiotemporal relationships between the particulate matter (P M2.5) with the other associated risk factors (e.g., socio-demographic, meteorological factors, and air pollutants). For this analysis, the geographically weighted regression (GWR)model with different kernels (viz. Gaussian and Bisquare kernels) and the ordinary least squares (OLS) model have been carried out to analyze the same from the perspective of the four major seasons (i.e., autumn, winter, summer, and monsoon) in different districts of India. It may be inferred from the results that the local model (i.e., GWR model with Bisquare kernel) captures the spatial heterogeneity in a better way with R2 values 0.994, 0.993, 0.992, 0.991, and 0.994respectively for four different seasons and for the corresponding 1-year cycle during October 2022-September 2023. The GWR model using the Bisquare kernel method performs better in terms of smaller corrected Akaike Information Criterion (AICc) (i.e., -896.883, -790.469, -618.686, -834.706, and -867.802 for four specific seasons and the corresponding 1-year cycle period respectively).