Geographically Distinct Expression Profile of Host Defense Peptides in the Skin of the Chinese Odorous Frog, Odorrana margaretae

Ling, Guiying; Li, Li; Gao, Jiuxiang; Yu, Haining; Wang, Yipeng; Jiang, Zhou

doi:10.3724/sp.j.1245.2013.00288

Cited by 3 publications

(2 citation statements)

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“…It showed 30.82% and 51.90% eradication rates at the concentration of 80 and 320 μg/mL, respectively. However, it has a slighter DPPH radical scavenging ability with the eradication rate of 10.36% at the concentration of 80 μg/mL 193 . The identification of an AOP antioxidin‐RL (AMRLTYNRPCIYAT) isolated from the skin secretions of frog Odorrana livida supports the idea that AOPs system is like to be widespread exist in the skin of amphibians.…”

Section: Sources Of Aopsmentioning

confidence: 55%

Antioxidant peptides, the guardian of life from oxidative stress

Zhu,

Wang,

Jia

et al. 2023

Medicinal Research Reviews

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Reactive oxygen species (ROS) are produced during oxidative metabolism in aerobic organisms. Under normal conditions, ROS production and elimination are in a relatively balanced state. However, under internal or external environmental stress, such as high glucose levels or UV radiation, ROS production can increase significantly, leading to oxidative stress. Excess ROS production not only damages biomolecules but is also closely associated with the pathogenesis of many diseases, such as skin photoaging, diabetes, and cancer. Antioxidant peptides (AOPs) are naturally occurring or artificially designed peptides that can reduce the levels of ROS and other pro‐oxidants, thus showing great potential in the treatment of oxidative stress‐related diseases. In this review, we discussed ROS production and its role in inducing oxidative stress‐related diseases in humans. Additionally, we discussed the sources, mechanism of action, and evaluation methods of AOPs and provided directions for future studies on AOPs.

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Section: Sources Of Aopsmentioning

confidence: 55%

Antioxidant peptides, the guardian of life from oxidative stress

Zhu,

Wang,

Jia

et al. 2023

Medicinal Research Reviews

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“…False lines, which may form during an unfavorable period in summer, are generally fainter than LAGs and do not form a complete ring around the bone section. We counted double lines in cross‐sections as 1 year of age; thus, they cannot affect the LAGs counted (Iturra‐Cid et al., 2010 ; Jiang et al., 2022 ; Khaloei et al., 2023 ; Phadmacanty et al., 2019 ; Yuan et al., 2021 ; Zhang et al., 2020 ).…”

Section: Methodsmentioning

confidence: 99%

Age structure and body size of two Tibetan toad (Bufo tibetanus) populations from different elevations in China

Xu,

Wang,

Liu

et al. 2024

Ecology and Evolution

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Understanding how age and body size vary across elevations can provide insights into the evolution of life‐history traits in animals. In the present study, we compared the demographic (using skeletochronology) and morphological traits of the Tibetan toad (Bufo tibetanus) between two populations from different elevational habitats (2650 vs. 3930 m). We found that (1) the mean age and body size of females were significantly greater than those of males in both populations; (2) both sexes of toads from the higher elevation tended to be significantly older in age and larger in body size; (3) there was a significant positive relationship between age and body size within each sex of the toad at both elevations; and (4) growth rates varied between the two populations, with the higher rate observed in the lower‐elevation population. Our results suggested that factors other than age, such as elevation‐associated temperature, influence the observed differences in body size between the two populations. Future research at a broader range of elevations should focus on these factors and evaluate their influence on animal growth patterns.

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Discovery of Antioxidant Peptides from Amphibians: A Review

Feng

Yang

et al. 2021

PPL

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: In recent years, bioactive peptide drugs as new drugs have attracted growing attention due to the increasing difficulty in developing new drugs with novel chemical structures. In addition, many diseases are linked to excessive oxidation in the human body. Therefore, the role of peptides with antioxidant activity in counteracting diseases related to oxidative stress is worth exploring. Amphibians are a major repository for bioactive peptides that protect the skin from biotic and abiotic stresses such as microbial infection and radiation injury. We characterized the first amphibian-derived gene-encoded antioxidant peptides in 2008. Since then, a variety of antioxidant peptides have been detected in different amphibian species. In this work, the physicochemical properties of antioxidant peptides identified from amphibians are reviewed for the first time, particularly acquisition methods, amino acid characteristics, antioxidant mechanisms, and application prospects. This review should provide a reference for advancing the identification, structural analysis, and potential therapeutic value of natural antioxidant peptides.

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Geographically Distinct Expression Profile of Host Defense Peptides in the Skin of the Chinese Odorous Frog, Odorrana margaretae

Cited by 3 publications

References 0 publications

Antioxidant peptides, the guardian of life from oxidative stress

Antioxidant peptides, the guardian of life from oxidative stress

Age structure and body size of two Tibetan toad (Bufo tibetanus) populations from different elevations in China

Discovery of Antioxidant Peptides from Amphibians: A Review

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