Geographic variation in allergic fungal rhinosinusitis

Ferguson, Berrylin J.; Barnes, Leon; Bernstein, Joel; Brown, David R.; Clark, Charles E.; Cook, Paul; DeWitt, Ward S.; Graham, Scott M.; Gordon, Bruce R.; Javer, Amin R.; Krouse, John H.; Kühn, Frederick A.; Levine, Howard L.; Manning, Scott C.; Marple, Bradley F.; Morgan, Alice H.; Osguthorpe, John D.; Skedros, Demetrius; Rains, B. Manrin; Ramadan, Hassan H.; Terrell, Jeffrey E.; Yonkers, Anthony J.

doi:10.1016/s0030-6665(00)80018-3

Cited by 155 publications

(116 citation statements)

References 12 publications

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“…For example, northern geographies typically have more patients with CRSsNP, in contrast to the southern temperate geographies which tend to have more patients with CRSwNP. 16,17 Second, we followed the rigorous methodology in the development of this instrument as described in the U.S. FDA Patient-Reported Outcome Measures. 8 Last, the physicians were blinded to the patients' self-assessment in order to avoid any bias with their assessment.…”

Section: Discussionmentioning

confidence: 99%

Qualitative development of the sinus control test: a survey evaluating sinus symptom control

Banglawala

Schlosser

Morella

et al. 2015

Int Forum Allergy Rhinol

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Section: Discussionmentioning

confidence: 99%

Qualitative development of the sinus control test: a survey evaluating sinus symptom control

Banglawala

Schlosser

Morella

et al. 2015

Int Forum Allergy Rhinol

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“…Previously, Aspergillus was thought to be the most common fungus responsible for allergic sinusitis, but it is now appreciated that disease due to dematiaceous fungi actually comprises the majority of cases (239,674). Geographic variation has also been reported, with an increased incidence in the southern United States (240).…”

Section: Phaeohyphomycosismentioning

confidence: 96%

Melanized Fungi in Human Disease

2010

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SUMMARY Melanized or dematiaceous fungi are associated with a wide variety of infectious syndromes. Many are soil organisms and are generally distributed worldwide, though certain species appear to have restricted geographic ranges. Though they are uncommon causes of disease, melanized fungi have been increasingly recognized as important pathogens, with most reports occurring in the past 20 years. The spectrum of diseases with which they are associated has also broadened and includes allergic disease, superficial and deep local infections, pneumonia, brain abscess, and disseminated infection. For some infections in immunocompetent individuals, such as allergic fungal sinusitis and brain abscess, they are among the most common etiologic fungi. Melanin is a likely virulence factor for these fungi. Diagnosis relies on careful microscopic and pathological examination, as well as clinical assessment of the patient, as these fungi are often considered contaminants. Therapy varies depending upon the clinical syndrome. Local infection may be cured with excision alone, while systemic disease is often refractory to therapy. Triazoles such as voriconazole, posaconazole, and itraconazole have the most consistent in vitro activity. Further studies are needed to better understand the pathogenesis and optimal treatment of these uncommon infections.

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“…925,1073,1079,1089 In the United States, associations with lower socioeconomic status, Southern geographic region, and African-American ethnicity have been identified. 925,1085,[1090][1091][1092] Controversy exists over the importance of type I hypersensitivity in AFRS pathophysiology, driving additional investigation. Humoral immunity and Ig-independent pathways may contribute.…”

Section: Viiig Crswnp and Afrs: Differences In Pathophysiologymentioning

confidence: 99%

International Consensus Statement on Allergy and Rhinology: Rhinosinusitis

Orlandi

Kingdom

Hwang

et al. 2016

Int Forum Allergy Rhinol

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541

877

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Background:The body of knowledge regarding rhinosinusitis (RS) continues to expand, with rapid growth in number of publications, yet substantial variability in the quality of those presentations. In an effort to both consolidate and critically appraise this information, rhinologic experts from around the world have produced the International Consensus Statement on Allergy and Rhinology: Rhinosinusitis (ICAR:RS). Methods:Evidence-based reviews with recommendations (EBRRs) were developed for scores of topics, using previously reported methodology. Where existing evidence was insufficient for an EBRR, an evidence-based review (EBR) was produced. The sections were then synthesized and the entire manuscript was then reviewed by all authors for consensus. Results:The resulting ICAR:RS document addresses multiple topics in RS, including acute RS (ARS), chronic RS (CRS) with and without nasal polyps (CRSwNP and CRSsNP), recurrent acute RS (RARS), acute exacerbation of CRS (AE-CRS), and pediatric RS. Conclusion:As a critical review of the RS literature, ICAR:RS provides a thorough review of pathophysiology and evidence-based recommendations for medical and surgical treatment. It also demonstrates the significant gaps in our understanding of the pathophysiology and optimal management of RS. Too o en the foundation upon which these recommendations are based is comprised of lowerlevel evidence. It is our hope that this summary of the evidence in RS will point out where additional research efforts may be directed. C 2016 ARS-AAOA, LLC. Key Words:rhinosinusitis; chronic rhinosinusitis; acute rhinosinusitis; recurrent acute rhinosinusitis; evidence-based medicine; systematic review; endoscopic sinus surgery List of Abbreviations Used

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Geographic variation in allergic fungal rhinosinusitis

Cited by 155 publications

References 12 publications

Qualitative development of the sinus control test: a survey evaluating sinus symptom control

Qualitative development of the sinus control test: a survey evaluating sinus symptom control

Melanized Fungi in Human Disease

International Consensus Statement on Allergy and Rhinology: Rhinosinusitis

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