Genus Styrax: A resource of bioactive compounds

Linh, Nguyen Thi Thuy; Tra, Nguyen Thanh; Hà, Nguyễn Thị Thu; Anh, Le Thị Tu; Cham, Ba Thi; Anh, Đang Thi Tuyet; Tuyen, Nguyen Van

doi:10.1016/b978-0-12-819487-4.00008-2

Cited by 16 publications

(7 citation statements)

References 76 publications

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“…Previous scholars have mainly explored methods for extracting DNA extraction methods from dried wood (Lobeliaceae), archaeological wood remains, ancient wood (oak), endangered wood (prismatic wood), and other samples. Although the DNA of wood may be severely degraded, DNA can be extracted through method optimization 54 – 57 . To date, resinous medicinal materials have been studied in Draconis sanguis (resin exuded from fruits) and agarwood (wood-containing resin) by improving DNA extraction methods 58 , 59 .…”

Section: Discussionmentioning

confidence: 99%

Successful identification of the species of the semipetrified amber medicinal resin benzoin using molecular diagnostic technology

Feng

Xie

et al. 2023

Sci Rep

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Benzoin is an incomplete lithified resin secreted from the trunk of the Styrax Linn. that is known as "semipetrified amber" and has been widely used in medicine due to its blood circulation-promoting and pain-relieving properties. However, the lack of an effective species identification method due to the numerous sources of benzoin resin and the difficulty of DNA extraction has led to the uncertainty of species of benzoin in the trade process. Here, we report the successful extraction of DNA from benzoin resin containing bark-like residues and the evaluation of commercially available benzoin species using molecular diagnostic techniques. By performing a BLAST alignment of ITS2 primary sequences and homology prediction analysis of ITS2 secondary structures, we found that commercially available benzoin species were derived from Styrax tonkinensis (Pierre) Craib ex Hart. and Styrax japonicus Sieb. et Zucc. of the genus Styrax Linn. In addition, some of the benzoin samples were mixed with plant tissues from other genera, accounting for 29.6%. Therefore, this study provides a new method to solve the problem of species identification of semipetrified amber benzoin using information from bark residues.

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Section: Discussionmentioning

confidence: 99%

Successful identification of the species of the semipetrified amber medicinal resin benzoin using molecular diagnostic technology

Feng

Xie

et al. 2023

Sci Rep

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“…Previous scholars have mostly explored DNA extraction methods from dried wood (Lobeliaceae), archaeological wood remains, ancient wood (oak), endangered wood (prismatic wood), etc. Although the DNA of wood may be severely degraded, DNA can be extracted through method optimization [54][55][56][57] . To date, resinous medicinal materials have been studied in Draconis sanguis (resin exuded from fruits) and Agarwood (wood-containing resin) by DNA extraction method improvement 58,59 .…”

Section: S Tonkinensis Y Discussionmentioning

confidence: 99%

Successful identification of the species of the semipetrified amber medicinal resin benzoin using DNA barcoding technology

Feng

Xie

et al. 2022

Preprint

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Benzoin, also known as semipetrified amber, is the resin secreted from the trunk of the benzoin plant. This medicinal material has blood circulation-promoting and pain-relieving properties. There are approximately 130 species of benzoin plants in the world, and the resin of many plants in the benzoin genus is used, so there is confounding of the species of origin. In this study, DNA was successfully extracted from the semipetrified amber medicinal material benzoin, and the species of benzoin in the medicinal herb market were evaluated by DNA barcoding. BLAST comparison of ITS2 primary sequences and homology prediction analysis of ITS2 secondary structures showed that the commercially available benzoin base originated from Styrax tonkinensis (Pierre) Craib ex Hart. and Styrax japonicus Sieb. et Zucc. of the genus Styrax Linn., and tissue from other genera was also detected to be mixed in with some samples, accounting for 29.6% of the samples. There is a risk that benzoin resin medical materials will be mixed with tissues from other plants. This is the first report on the subject, and the approach taken provides technical feasibility for the identification of the basis of the benzoin resin medical materials.

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“…Phytochemical and pharmacological studies of medicinal plants have made substantial progress in recent years, with an emphasis on novel molecules with therapeutic qualities. 11–17 The focus of this section is on publications over the last 40 years that deal with phytochemical investigations of Tupistra species. Up to now, approximately 200 compounds with diverse chemical structures have been isolated from the Tupistra genus, but steroid derivatives have predominated.…”

Section: Phytochemistrymentioning

confidence: 99%

Genus Tupistra: A Comprehensive Review of Phytochemistry and Pharmacological Activity

Linh

Son

2022

Natural Product Communications

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In the current paper, secondary metabolites separated from Tupistra plants have been reviewed. Approximately 200 phytochemicals, classified in various chemical classes of bioactive compounds, have been compiled, along with their sources and references. The most striking feature is that the most frequently isolated compounds have been spirostanol sapogenins, and spirostanol and furostanol saponins, most of which are new in nature. The application of both Tupistra plant extracts and isolated compounds in biological assays is also one of the crucial aims in pharmacological discoveries. Tupistra constituents have demonstrated valuable properties in the field of pharmacology, such as antioxidative, antimicrobial, antidiabetic, and antihepatic activities, but their cytotoxic and anti-inflammatory actions can be considered as the more remarkable. In vivo cancer-related activities of the tested Tupistra samples were mostly based on apoptosis. Further phytochemical investigations, together with extensive assessments of the biological profiles and mechanism of action studies of the components of Tupistra species are to be expected.

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Genus Styrax: A resource of bioactive compounds

Cited by 16 publications

References 76 publications

Successful identification of the species of the semipetrified amber medicinal resin benzoin using molecular diagnostic technology

Successful identification of the species of the semipetrified amber medicinal resin benzoin using molecular diagnostic technology

Successful identification of the species of the semipetrified amber medicinal resin benzoin using DNA barcoding technology

Genus Tupistra: A Comprehensive Review of Phytochemistry and Pharmacological Activity

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