Genotyping-by-sequencing targets genic regions and improves resolution of genome-wide association studies in autotetraploid potato
Sanjeev Kumar Sharma,
Karen McLean,
Peter E. Hedley
et al.
Abstract:Key message
De novo genotyping in potato using methylation-sensitive GBS discovers SNPs largely confined to genic or gene-associated regions and displays enhanced effectiveness in estimating LD decay rates, population structure and detecting GWAS associations over ‘fixed’ SNP genotyping platform. Study also reports the genetic architectures including robust sequence-tagged marker–trait associations for sixteen important potato traits potentially carrying higher transferability across a wider ra… Show more
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