2018
DOI: 10.1007/s00705-018-3759-0
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Genotypic variability analysis of DENV-1 in Mexico reveals the presence of a novel Mexican lineage

Abstract: Here, we report for the first time the circulation of dengue virus type 1 (DENV-1) belonging to the lineage IV of genotype V (African American genotype) based on phylogenetic analysis of nucleotide sequences from 10 DENV-1-positive samples obtained in Mexico between 2012 and 2014. Our data revealed that the lineages III and IV of DENV-1 genotype V were found circulating during the same period, probably explaining the rise in the number of cases of severe dengue during that period.

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Cited by 5 publications
(3 citation statements)
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“…Symptoms related to orthopedics, psychiatry and ophthalmology have been documented in previous studies [12,13] . The ocular symptoms experience by VDTs users typically include eyestrain, eye fatigue, burning sensations, irritation, redness, blurred vision and dry eyes [7,14,15] .…”
Section: Introductionmentioning
confidence: 82%
“…Symptoms related to orthopedics, psychiatry and ophthalmology have been documented in previous studies [12,13] . The ocular symptoms experience by VDTs users typically include eyestrain, eye fatigue, burning sensations, irritation, redness, blurred vision and dry eyes [7,14,15] .…”
Section: Introductionmentioning
confidence: 82%
“…Furthermore, most of the dengue cases in the last 10 years were reported from the northern states of Mexico, where DENV-1 and DENV-2 are the predominant serotypes. The DENV-1 isolate from this study clustered with other Mexican and Central American strains of DENV-1 belonging to genotype V. DENV-1 genotype V has been circulating in Mexico since the late 1970s and has experienced several lineage replacements since its introduction, causing a high degree of genetic variability [ 9 ]. Moreover, DENV-1 genotype V is widely distributed in the Americas, and its clades are associated with distinct regions (South America, Caribbean, and Central America) [ 10 ].…”
Section: Discussionmentioning
confidence: 99%
“…A clear example of In-DRE's contribution was the characterization of a highly pathogenic avian A influenza strain (H7N3) in poultry farm workers from Jalisco. 10 The transmission of the chikungunya 11 , Zika 12 , and dengue 13 viruses in our country was also studied, the circulation of non-polio D68 enterovirus was identified in respiratory conditions and the diagnosis of influenza in children was ruled out at the Institute. 14 Detection of the Aedes mosquito in Mexico City 15 triggered focused monitoring and surveillance activities.…”
Section: Epidemic Outbreaksmentioning
confidence: 99%