Genotypes and drug resistance patterns of multi-drug-resistant<i>mycobacterium tuberculosis</i>strains in Pakistan

Javed, Hasnain; Jamil, Nazia

doi:10.1183/13993003.congress-2015.pa2687

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“…TB countries 6 . The World Health Organization (WHO) reported an estimated incindence of 275 cases per 100,000 persons and prevalence of 342 cases per 100,000 population 7,8 . In case of diabetes mellitus, the WHO has reported 4.3 million affected individuals in Pakistan and it is included among the top ten countries with highest DM incidence and it is expected that this figure will reach 14.5 million by the end of year 2025.…”

Section: Introductionmentioning

confidence: 99%

Diabetes mellitus among tuberculosis patients: a cross sectional study from Pakistan

Tahir¹,

Ahmad²,

Akhtar

et al. 2017

Afr H. Sci.

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Background: The co-occurrence of diabetes mellitus (DM) and tuberculosis (TB) is largely associated with high frequency of morbidity. Objective: To determine the prevalence of DM among TB patients and describe the socio-demographic and behavioral factors associated with TB-DM co-occurrence . Methods: We enrolled 500 TB patients from September, 2014 to August 2015 at four major public sector hospitals of Lahore, Pakistan. A questionnaire was used to collect information regarding associated socio-demographic and behavioral factors of the patients. We monitored the fasting blood sugar of each patient by using a semi automated clinical chemistry analyzer followed by an HbA1c level check of all hyperglycemic patients. Results: The prevalence of TB-DM co-occurrence was 14.8%. The prevalence of TB-DM was higher (62.2%) among males. The >57 year age group had the highest proportion of patients (35.1%), with co-existent TB-DM. Most were illiterate (73.0%) and unemployed (48%). Moreover, among the 74 patients positive for TB-DM had a history of smoking. Age and education level were significantly associated with DM-TB while gender, occupation and smoking were not associated. Conclusion:The study revealed a 14.8% prevalence of DM among TB patients. This was associated with several socio-demographic factors, including age, unemployment, literacy and polluted environment. Thus, poor and unhealthy lifestyles were the factors associated with DM among immunologically compromised individuals due to TB. Keywords: Tuberculosis (TB), diabetes mellitus (DM), socio-demographic and behavioral factors.

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Section: Introductionmentioning

confidence: 99%