Genotype Screening of Bovine Brachyspina in Taiwan Holstein Cows

Chao, Chun Hsuan; Lee, Kuo Hua

doi:10.3844/ajavsp.2020.206.210

Cited by 6 publications

(2 citation statements)

References 8 publications

(14 reference statements)

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“…In addition to the aforementioned uses, genotyping enables genetic defect detection and parentage identification. We recently analyzed the carrier frequencies of the genetic defect brachyspina, bovine leukocyte adhesion deficiency, complex vertebral malformation, deficiency of uridine monophosphate synthase, and mule foot in Holstein cows in Taiwan, and we corrected contrasting cases of the brachyspina genotype (Chao et al 2020(Chao et al , 2021. The International Society for Animal Genetics (ISAG) approved standards for genotyping laboratories to conduct parentage verification in 2012.…”

Section: Introductionmentioning

confidence: 99%

Polish Journal of Veterinary Sciences

Chao

Yeh

Chen

et al. 2022

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Information regarding the correct pedigree of and relationship between animals is useful for managing dairy breeding, reducing inbreeding, estimating breeding value, and establishing correct breeding programs. Additionally, the successful implementation of progeny testing is crucial for improving the genetics of dairy cattle, which depends on the availability of correct pedigree information. Incorrect pedigree information leads to bias in bull evaluation. In this study, Neogen GeneSeek Genomic Profiler (GGP) 50K SNP chips were used to identify and verify the sire of Taiwanese Holstein dairy cattle and analyze the reasons that lead to incorrect sire records. Samples were collected from 2,059 cows of 36 dairy farms, and the pedigree information was provided by breeders. The results of sire verification can be divided into three categories:

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Section: Introductionmentioning

confidence: 99%

Polish Journal of Veterinary Sciences

Chao

Yeh

Chen

et al. 2022

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“…It's a high throughput and uses a popular allele discrimination method to generate allele specific products [3,4]. We recently analyzed carrier frequencies of the genetic defect bovine brachyspina [BS] in the Holstein cows in Taiwan and corrected the contrasting case of brachyspina genotype [5].…”

Section: Introductionmentioning

confidence: 99%

Simultaneous Genetic Screening of Bovine Leukocyte Adhesion Deficiency, Complex Vertebral Malformation, Deficiency of Uridine Monophosphate Synthase, and Mule foot in Holstein Cows in Taiwan

Chao¹

2021

APDV

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This study analyzed the prevalence of genetic defect carriers of Bovine Leukocyte Adhesion Deficiency [BLAD], Complex Vertebral Malformation [CVM], Deficiency of Uridine Monophosphate Synthase [DUMPS], and mule foot in the Holstein cow population in Taiwan. In total, 1688 cows from 31 herds were analyzed and 9 [0.53%] and 30 [1.78%] were BLAD and CVM carriers, respectively. No DUMPS or mule foot carriers were discovered. Frozen semen of genetic defect-carrying bulls is no longer imported to Taiwan in accordance with import restrictions on frozen bull semen implemented in 2005. However, pedigree analysis revealed that some defective alleles remain in Taiwanese dairy herds because of the mating program. The main source of the defect genotype is dam carriers. Close monitoring is thus necessary for eliminating the recessive genetic defects from the Holstein cattle population in Taiwan.

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