Genotype profiles for the Costa Rican population at 7 PCR-based loci

Morera-Brenes, Bernal; Morales, Cynthia; Jiménez-Arce, Gerardo

doi:10.15517/rbt.v1i2.15398

Cited by 2 publications

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“…Se contribuyó con los esfuerzos por impulsar el desarrollo de la genética aplicada a las ciencias forenses en Iberoamérica, por medio de la presentación de nueve ponencias en congresos de carácter nacional de Microbiología y Medicina en Costa Rica, y en congresos internacionales de Biología Molecular y Ciencias Forenses en Panamá, El Salvador y España, para dar a conocer los avances y logros del proyecto, y con la publicación de nueve trabajos científicos (Morales 1995a, b, Morales y Marín Rojas 1997, Morera y Jiménez-Arce 1998, Jiménez-Arce y , Morales-Cordero et al 1999, 2004. Sin embargo, hay que tener presente que Costa Rica dista mucho de estar a la cabeza en la investigación y desarrollo de las ciencias forenses, ni siquiera al nivel regional más inmediato (Morales et al 2000, Morales 2002.…”

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La implementación forense de la tecnología del ADN en Costa Rica: Un análisis retrospectivo

Morera-Brenes

Jiménez-Arce

2014

RBT

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Section: Otros Logros Del "Proyecto De Adn"unclassified

La implementación forense de la tecnología del ADN en Costa Rica: Un análisis retrospectivo

Morera-Brenes

Jiménez-Arce

2014

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Investigation of KIF6 Trp719Arg in a Case-Control Study of Myocardial Infarction: A Costa Rican Population

Bare¹,

Ruiz-Narváez

Tong³

et al. 2010

PLoS ONE

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Background and MethodologyThe 719Arg allele of KIF6 (rs20455) was associated with coronary events in Caucasian participants of five prospective studies. We investigated whether this KIF6 variant was associated with non-fatal myocardial infarction (MI) in a case-control study of an admixed population from the Central Valley of Costa Rica. Genotypes of the KIF6 variant were determined for 4,134 men and women. Cases (1,987) had survived a first MI; controls (2,147) had no history of MI and were matched to cases by age, sex, and area of residence. We tested the association between the KIF6 719Arg allele and non-fatal MI by conditional logistic regression and adjusted for admixture of founder populations.Principal FindingsCompared with the reference Trp/Trp homozygotes, KIF6 719Arg carriers were not at significantly higher risk for non-fatal MI in this study after adjustment for traditional risk factors or admixture (OR = 1.12; 95%CI, 0.98–1.28). Heterozygotes of the KIF6 Trp719Arg variant were at increased risk of non-fatal MI: the adjusted odds ratio was 1.16 (95% confidence interval, 1.01–1.34), but this association would not be significant after a multiple testing correction.Conclusions/SignificanceWe found that carriers of the KIF6 719Arg allele were not at increased risk of non-fatal MI in a case-control study of Costa Ricans living in the Central Valley of Costa Rica.

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Genotype profiles for the Costa Rican population at 7 PCR-based loci

Abstract: Complete electronic DNA profiles of 2006 randomly selected Costa Ricans, typed for 7 PCR-based loci, are presented. Such data may prove valuable for anthropological and forensic studies of the Costa Rican population. Rev. Biol. Trop. 52(3): 713-715. Epub 2004 Dic 15.

Cited by 2 publications

References 20 publications

La implementación forense de la tecnología del ADN en Costa Rica: Un análisis retrospectivo

La implementación forense de la tecnología del ADN en Costa Rica: Un análisis retrospectivo

Investigation of KIF6 Trp719Arg in a Case-Control Study of Myocardial Infarction: A Costa Rican Population

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