Genotoxic Effects of Environmental Pollutant Heavy Metals on Alburnus chalcoides (Pisces: Cyprinidae) Inhabiting Lower Melet River (Ordu, Turkey)

Abstract

The lower Melet River is a drinking water source that is surrounded by hazelnut grove, agricultural lands, resulting in the accumulation of genotoxic agents such as mining activities, various domestic and agricultural wastes. Therefore, it receives many domestic and agricultural wastes that contain the genotoxic agent. This study was aimed to assess the heavy metal concentrations in water, sediment, and bioaccumulation in the tissues of Alburnus chalcoides. Comet assay and micronucleus test were used to evaluate the genotoxic effects on the blood cells of A. chalcoides. The concentrations of heavy metals and metalloid in the water, in the sediments and in the muscle of fish were in the

Genotoxic effect of heavy metals on Astyanax lacustris in an urban stream

“…Several studies have shown that aquatic organisms exposed to water and sediments contaminated by heavy metals can exhibit genotoxic effects ( Turan et al., 2020 ; Kontaş and Bostancı, 2020 ). Besides, Viana et al.…”

“…Several studies have shown that aquatic organisms exposed to water and sediments contaminated by heavy metals can exhibit genotoxic effects (Turan et al, 2020;Kontaş and Bostancı, 2020). Besides, Viana et al (2018) reported that A. lacustris from impacted sites had higher concentrations of Pb, Cu, Fe, Zn, and Ni in muscle tissue and higher frequency of micronucleus.…”

Environmental DNA and RNA as Records of Human Exposome, Including Biotic/Abiotic Exposures and Its Implications in the Assessment of the Role of Environment in Chronic Diseases

“…The use of eDNA analysis of aquatic and terrestrial organisms provide information about not only the relationships between species, but also genomic and epigenomic patterns of each organism over space and time, and their responses to environmental change [ 43 ]. Longitudinal analysis of linkages of organisms ranging from microorganisms to mammals in a marine setting using high-throughput sequencing of multiple conserved genetic markers from eDNA showed dynamic relationships between marine ecosystem and environmental variables over time [ 44 , 45 ]. A recent study of exposure of heavy metals from anthropogenic sources on the DNA integrity showed that heavy metals and metalloid in the water from the polluted location produce genotoxic damages to a fish species, Alburnus chalcoides [ 46 ].…”

In vivo assessment of genotoxic effects in Cyprinus carpio L., 1758 (Teleostei: Cyprinidae) exposed to selected metal(oid)s

“…It was reported that the increase of metal(oids) such as aluminum, arsenic, and manganese in water and sediment in the Melet River caused genotoxic damage in the Alburnus chalcoides , Capoeta banarescui , and Vimba vimba and threatens the life of the fish. In addition, these contaminated fish consumed by people in this region can threaten human health (Kontaş, 2018).…”

“…Aquatic toxicology research enables the estimation of the negative effects of biological, chemical, or physical agents on aquatic organisms and ecosystems and establish the basis of necessary conservation policies (Nikinmaa, 2014). In recent years, detailed evaluation using the comet assay, micronucleus test, nuclear abnormalities of the genotoxic effects of metalloid and heavy metals for different groups such as drinking water, fish, and other organisms has further increased the popularity of these toxicological studies (Doğanlar et al, 2016; Gökalp et al, 2020; Kontaş and Bostancı, 2020; Stankevičiūtė et al, 2021). In addition, the effects of metal(oid)s on aquatic organisms, ecosystems, and human health need to be investigated using genotoxicity tests (Lah et al, 2005; Gökalp et al, 2020).…”