Genomics and Systems Biology at the “Century of Human Population Genetics” conference

Abstract

This special issue of BMC Genomics presents works in the broad field of genomics as discussed at the "Century of Human Population Genetics" conference in Moscow in May 2019, held at Moscow State University (http:// centenary-popgene.com/). The Conference discussed the current research of gene pools of the world's nations, analysis of ancient DNA, judicial possibilities of human genetics, developemngt of population genetic databases, biobanks, as well as a set of newest additions to the toolbox of genomics technologies. It was an unique event, dedicated to the 100th anniversary of the first human population study performed in 1919, way before a function of DNA was discovered. This journal issue also contains materials on human genomics and computational genetics presented at the "Systems Biology and Bioinformatics" (SBB-2019), a School for the Young Scientists held in Novosibirsk, Russia. Since 2008, this traditional school on bioinformatics is organized annually, under joint guidance of the Institute of Cytology and Genetics of the Siberian Branch of the Russian Academy of Sciences and the Novosibirsk State University (http://conf.bionet.nsc.ru/sbb2019/en/) [1, 2]. Traditionally, the Program Committee selects best conference materials for subsequent publications in BMC Genomics and related journals of BioMed Central [3-6]. The SBB Schools in Novosibirsk are the satellite events for the larger BGRS\SB (Bioinformatics of Genome

Medical Genetics, Genomics and Bioinformatics Aid in Understanding Molecular Mechanisms of Human Diseases

“…New biomarkers derived from the transcriptomics analysis or standalone mining of associative networks aim to aid physicians to consider individual cases. The current series of post-conference journal Special Issues started with a coverage of Bioinformatics of Genome Regulation and Structure (BGRS) conferences and related Schools on Systems Biology and Bioinformatics (SBB) held in Novosibirsk, Russia [ 2 , 3 , 4 , 5 , 6 ]. This particular Special Issue contains the manuscripts that have followed on from oral and poster presentations discussed at the “Systems biology, bioinformatics and biomedicine” (SbioMed-2020) symposium in Novosibirsk, as well as the conferences at I.M.…”

“…This particular Special Issue contains the manuscripts that have followed on from oral and poster presentations discussed at the “Systems biology, bioinformatics and biomedicine” (SbioMed-2020) symposium in Novosibirsk, as well as the conferences at I.M. Sechenov First Moscow State Medical University in Moscow [ 6 ]. The majority of these papers present some insights into the molecular mechanisms of various human diseases, and their progression.…”

Recent Trends in Cancer Genomics and Bioinformatics Tools Development

“…For our overview of recent advances in biomedical frontiers, we acknowledge the medical summit SIBS (Sechenov International Biomedical Summit) organized at I.M. Sechenov First Moscow State Medical University (https://sechenov-sibs.confreg.org/), and other international meetings in Moscow such as "Centenary of human population genetics" [8][9][10] and MGNGS (Medical Genetics-Next-Generation sequencing) (http: //ngs.med-gen.ru/) [11]. Over the last two years, many traditional international conferences have been postponed or held online, which has also led to publication delays.…”

Bioinformatics Applications to Reveal Molecular Mechanisms of Gene Expression Regulation in Model Organisms

“…The current series of post-conference journal Special Issues started with the coverage of the Bioinformatics of Genome Regulation and Structure (BGRS) [ 4 , 5 , 6 ] conferences and the related Schools on Systems Biology and Bioinformatics (SBB) held in Novosibirsk, Russia [ 7 , 8 ], and it was later completed by other international conferences on genetics, such as the Belyaev Conference—2017 [ 9 ] and “Centenary of Human Population Genetics” in 2019 [ 10 , 11 ]. The papers in this issue present novel bioinformatics models on gene expression regulation, alternative splicing, chromatin immunoprecipitation-sequencing (ChIP-seq) technology to analyze transcription factor (TF) binding to DNA, as well as some insights into the molecular mechanisms of human diseases.…”