Genomic Selection as a Basis of Breeding (Review)

Kalashnikov, A. E.; Golubkov, Anatoly I.; Trufanov, Victor G.; Gosteva, E. R.; Yaluga, V. L.; Прожерин, В П

doi:10.36718/1819-4036-2021-7-163-170

Cited by 2 publications

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“…2 , канд.биол.наук Хамзин С.В. 2 , бакалавр 1 Санкт-Петербургский филиал Всероссийского научно-исследовательского института рыбного хозяйства и океанографии, Россия 2 Санкт-Петербургский государственный университет ветеринарной медицины, Россия РЕФЕРАТ Исследования показали, что поступление металлов и других загрязняющих веществ аэрогенным путем в Ладожское озеро связано с наличием как удаленных, так и местных источников поступления в атмосферу. В этом отношении Ладожское озеро находится в уязвимом состоянии, что показали исследования -так как нередко содержание металлов в атмосферных осадках выше, чем в воде.…”

Section: Evaluation Of the Breeding Value Of Sires In The Breeding Re...unclassified

Evaluation of the breeding value of sires in the breeding reproducer of the Kholmogory breed of cattle

Olontsev¹,

Ukolov

Sharaskina

2023

jour

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Estimates of the breeding value of producers and breeding stock of cattle use various information and analytical models and statistical methods, including the determination of the breeding value of animals using the BLUP methodology and the BLUP AM methodology, for the subsequent transition to predictive genomic SNP selection. The study was conducted on the reproductive population of cows of the Kholmogory breed of the Arkhangelsk region, Kholmogory district. A genealogical analysis of a spontaneous population of cows of first-calf heifers of the Kholmogory breed was carried out, represented by the offspring of 66 bulls, which were evaluated according to the main productive indicators and breeding value (PC). A rank assessment of sires was carried out according to the efficiency of the productive contribution of daughters, bulls' PC for milk yield and MJ, MDB. The studies confirmed the literature data on the possibility and effectiveness of using phantom cattle populations in assessing the breeding value of producers.

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Section: Evaluation Of the Breeding Value Of Sires In The Breeding Re...unclassified

Evaluation of the breeding value of sires in the breeding reproducer of the Kholmogory breed of cattle

Olontsev¹,

Ukolov

Sharaskina

2023

jour

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Genetic mechanisms of bacteria recognition by cattle innate immunity receptors

Kalashnikov,

Gosteva,

Shchegolkov

et al. 2023

Vestn. Novosib. gos. agrar. univ.

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The research identified a list of molecules involved in the mechanisms of innate immunity in cattle and the recognition of bacterial pathogens. The current list of molecular receptors has expanded to include TLR receptors and the recently defined NOD-like receptors (NLRs): NOD, NALP, NAIP, and IPAF. TLR molecules are designed to transmit a ligand-binding signal on the cell surface or endosome and activate specific molecules of bacterial origin in the cytosol, such as peptidoglycans, RNA, toxins and flagellins. The obtained data on the molecular structure of TLR and NLR receptors indicate their anti-inflammatory role, mediated by signals through nuclear transcription factor κB and activation of caspase-1 in the inflammasome. It has been shown that the role of immunosensors of extracellular and intracellular perception of bacteria in regulating inflammation is synergistic. Mutations in TLR and NOD receptors are associated with autoimmune inflammatory syndromes. This review examines the body's ways of recognising intracellular pathogens, describes the problem of their mimicry from the animal immune system, and the molecular mechanisms of such interactions. Variants of molecular interactions of innate immune receptors with peptidoglycans, bacterial DNA and toxins, cell wall compartments, and bacterial flagellin receptors are also considered. This study aimed to analyse the current understanding of the genetic and molecular structure of the immune response to bacterial environmental factors and the mechanisms and characteristics of the reaction of the animal body.

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Genomic Selection as a Basis of Breeding (Review)

Cited by 2 publications

References 0 publications

Evaluation of the breeding value of sires in the breeding reproducer of the Kholmogory breed of cattle

Evaluation of the breeding value of sires in the breeding reproducer of the Kholmogory breed of cattle

Genetic mechanisms of bacteria recognition by cattle innate immunity receptors

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