Genomic heterozygosity is associated with a lower risk of osteoarthritis
Robert Gill,
Ming Liu,
Guang Sun
et al.
Abstract:Background
Genomic heterozygosity has been shown to confer a health advantage in humans and play a protective role in complex diseases. Given osteoarthritis (OA) is a highly polygenic disease, we set out to determine if an association exists between OA and genomic heterozygosity.
Results
End-stage knee and hip OA patients and healthy controls were recruited from the Newfoundland and Labrador (NL) population. The Arthritis Research UK Osteoarthritis… Show more
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