Genomic breeding for food, environment and livelihoods

Rivers, John; Warthmann, Norman; Pogson, Barry J.

doi:10.1007/s12571-015-0431-3

Cited by 24 publications

(16 citation statements)

References 61 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A number of recent reviews analyze the potential benefit of the Omics technologies to agricultural productivity and highlight various limitations that need to be addressed [19,27,52,115].…”

Section: Molecular Breedingmentioning

confidence: 99%

“…Utilization of molecular technologies that have revolutionized commercial crop breeding can be used as a proof of concept for adoption of such genomics-based prediction methodologies [122,123] to improve trait performance in other less-studied crops [115,116]. These approaches are being adopted in crops of importance in developing countries such as in maize and wheat [121], rice [124], pulses (legumes) [11], cassava [118,120], cowpea [125], lentil [126], soybean [127,128], and pigeon pea [129].…”

Section: Molecular Breedingmentioning

confidence: 99%

“…Genetic improvement is heralded as the best option to enhance crop productivity, resilience to climate effects, and nutritional quality. The effective and efficient application of advanced biosciences tools and products holds substantial promise for enhanced agricultural productivity, improved livelihoods, and better prospects for food and nutrition security in Africa, where less-studied crops are grown as staples [114,115,158]. Genomics-enabled breeding will enable scientists to more effectively tap into the wealth of genetic variation in landraces and wild relatives for novel traits.…”

Section: Conclusion: Prospects and Perspectivesmentioning

confidence: 99%

See 2 more Smart Citations

Perspectives on the Application of Next-generation Sequencing to the Improvement of Africa’s Staple Food Crops

Gedil¹,

Ferguson²,

Girma³

et al. 2016

Next Generation Sequencing - Advances, Applications and Challenges

View full text Add to dashboard Cite

The persistent challenge of insufficient food, unbalanced nutrition, and deteriorating natural resources in the most vulnerable nations, characterized by fast population growth, calls for utilization of innovative technologies to curb constraints of crop production. Enhancing genetic gain by using a multipronged approach that combines conventional and genomic technologies for the development of stress-tolerant varieties with high yield and nutritional quality is necessary. The advent of nextgeneration sequencing (NGS) technologies holds the potential to dramatically impact the crop improvement process. NGS enables whole-genome sequencing (WGS) and re-sequencing, transcriptome sequencing, metagenomics, as well as high-throughput genotyping, which can be applied for genome selection (GS). It can also be applied to diversity analysis, genetic and epigenetic characterization of germplasm and pathogen detection, identification, and elimination. High-throughput phenotyping, integrated data management, and decision support tools form the necessary supporting environment for effective utilization of genome sequence information. It is important that these opportunities for mainstreaming innovative breeding strategies, enabled by cutting-edge "Omics" technologies, are seized in Africa; however, several constraints must be addressed before the benefit of NGS can be fully realized. African breeding programs must have access to high-throughput genotyping facilities, capacity in the application of genome selection and marker-assisted breeding must be built and supported by capacity in genomic analysis and bioinformatics. This chapter demonstrates how interventions with NGS-enabled innovative strategies can be applied to increase genetic gain with insights from the Consortium of International

show abstract

“…A number of recent reviews analyze the potential benefit of the Omics technologies to agricultural productivity and highlight various limitations that need to be addressed [19,27,52,115].…”

Section: Molecular Breedingmentioning

confidence: 99%

Section: Molecular Breedingmentioning

confidence: 99%

Section: Conclusion: Prospects and Perspectivesmentioning

confidence: 99%

See 1 more Smart Citation

Perspectives on the Application of Next-generation Sequencing to the Improvement of Africa’s Staple Food Crops

Gedil¹,

Ferguson²,

Girma³

et al. 2016

Next Generation Sequencing - Advances, Applications and Challenges

View full text Add to dashboard Cite

show abstract

“…Successful efforts to supply sufficient food will include closing yield gaps in lower income countries, in part by increasing the use of better seeds and fertilizer, improving resource management, and enhancing the technology of crop production through advances in genomics and phenomics [9][10][11][12][13]. In addition, public officials must choose policies and investments that encourage increases in agricultural productivity on large and small farms, and in irrigated and rainfed settings [14][15][16].…”

Section: Open Accessmentioning

confidence: 99%

Achieving Water and Food Security in 2050: Outlook, Policies, and Investments

Wichelns

2015

Agriculture

View full text Add to dashboard Cite

Food production in 2050 will be sufficient, globally, but many of the poor will remain food insecure. The primary cause of food insecurity will continue to be poverty, rather than inadequate food production. Thus, policies and investments that increase the incomes of the poor will remain the best ways to extend food security to all. Investments that promote growth in sustainable agriculture and provide non-farm employment opportunities in rural areas of lower income countries will be most helpful. There will be sufficient water, globally, to achieve food production goals and sustain rural and urban livelihoods, if we allocate and manage the resource wisely. Yet, water shortages will constrain agricultural production and limit incomes and livelihood opportunities in many areas. Policies and investments are needed to extend and ensure access to water for household use and agricultural production. Challenges requiring the attention of policy makers and investors include increasing urbanization and increasing demands for land and water resources. Policy makers must ensure that farmers retain access to the water they need for producing food and sustaining livelihoods, and they must create greater opportunities for women in agriculture. They must also motivate investments in new technologies that will enhance crop and livestock production, particularly for smallholders, and encourage the private sector to invest in activities that create employment opportunities in rural areas.

show abstract

“…Genomic selection relies on screening prospective crops for genetic markers that are known to confer desirable physical traits before the crops are grown, thereby fast-tracking the plant-breeding process 3 , while also avoiding artificial modification of crop genetics (that is, genome modification). Widespread adoption of genomic selection in plant-breeding hinges on rapid, flexible, high-throughput, and cost-effective genotyping technologies 4 .…”

Section: Introductionmentioning

confidence: 99%

Programmable microfluidic genotyping of plant DNA samples for marker-assisted selection

et al. 2018

View full text Add to dashboard Cite

As demands to maintain the global food production continue to mount, multinational seed companies are turning to new DNA marker technologies to accelerate the rate of plant breeding and crop improvement. The key to widespread adoption of molecular breeding is the availability of flexible and cost-effective tools that can perform combinatorial and high-throughput genotyping of single-nucleotide polymorphisms (SNPs) to guide the crop development process. Toward this end, we have developed a programmable, droplet-based microfluidic device for genotyping maize genomic DNA. A unique feature of the microfluidic platform is the nano sample processors (NSPs), which allow the device to sequentially load an unrestricted number of unique DNA samples using only two inlets, overcoming the current limitation to the number of sample inputs due to small device footprint. Direct and programmable droplet generation within the device allows each sample to be genotyped against a panel of markers on demand. Moreover, we have successfully implemented the Invader assay for SNP genotyping in flowing, 50-nL droplets, thus achieving significant reduction in consumption of reagents per reaction as compared with conventional genotyping platforms. As a demonstration, we performed 240 Invader reactions (testing 8 DNA samples against 10 SNP markers) and achieved greater than 93% accuracy in SNP calling of plant DNA samples in a single droplet-based experiment.

show abstract

Genomic breeding for food, environment and livelihoods

Cited by 24 publications

References 61 publications

Perspectives on the Application of Next-generation Sequencing to the Improvement of Africa’s Staple Food Crops

Perspectives on the Application of Next-generation Sequencing to the Improvement of Africa’s Staple Food Crops

Achieving Water and Food Security in 2050: Outlook, Policies, and Investments

Programmable microfluidic genotyping of plant DNA samples for marker-assisted selection

Contact Info

Product

Resources

About