Abstract:To study the frequency and spectrum of fetal chromosomal abnormalities in pregnant women, depending on age, a cytogenetic study of 2248 biopsies of the chorion and placenta, cord blood lymphocytes and amniocytes was carried out in 2016-2020. The work used the generally accepted methods of direct preparation of chromosome preparation and methods of cell cultivation. The analysis of the preparations was performed based on GTG, CBG staining method and FISH method, using DNA probes for centromeric regions 13, 18, … Show more
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