Genomic Analysis of Lymphoma Risk in Bullmastiff Dogs
Sally A. Mortlock,
Monica C. Asada,
Pamela Xing Yi Soh
et al.
Abstract:Lymphoma is the most common haematological malignancy affecting dogs and has a high incidence in the Bullmastiff breed. The aim of this study was to identify risk loci predisposing this breed to the disease. The average age of lymphoma diagnosis in 55 cases was less than 6 years, similar to the median age of 64 cases from our clinical and pathology databases. When fine-scale population structure was explored using NETVIEW, cases were distributed throughout an extended pedigree. When genotyped cases (n = 49) an… Show more
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