Genome wide scan for quantitative trait loci affecting tick resistance in cattle (Bos taurus × Bos indicus)

Machado, M. A.; Azevedo, Ana Luisa Sousa; Teodoro, R. L.; Pires, M.A.; Peixoto, Maria Gabriela Campolina Diniz; Freitas, Célio de; Prata, Márcia Cristina de Azevedo; Furlong, John; Silva, Marcos Vinícius Gualberto Barbosa da; Guimarães, Simone Eliza Facioni; Regitano, Luciana Correia de Almeida; Coutinho, Luiz Lehmann; Gasparin, G.; Verneque, R.S.

doi:10.1186/1471-2164-11-280

Cited by 56 publications

(65 citation statements)

References 40 publications

(37 reference statements)

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“…Detailed information regarding this population, including breeding schemes, phenotypic evaluation, and genetic value evaluation processes, was described by Machado et al (2010). Briefly, all animals were ranked by the predicted genetic value for tick resistance.…”

Section: Experimental Animalsmentioning

confidence: 99%

Expression of immune response genes in peripheral blood of cattle infested with Rhipicephalus microplus

Domingues¹,

Wohlres-Viana²,

Reis³

et al. 2014

Genet. Mol. Res.

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ABSTRACT. The bovine tick Rhipicephalus microplus is responsible for severe economic losses in tropical cattle production. Bos indicus breeds are more resistant to tick infestations than are Bos taurus breeds, and the understanding of the physiological mechanisms involved in this difference is important for the development of new methods of parasite control. We evaluated differences in the transcript expression of genes related to the immune response in the peripheral blood of cattle previously characterized as resistant or susceptible to tick infestation. Crossbreed F2 Gir x Holstein animals (resistant, N = 6; susceptible, N = 6) were artificially submitted to tick infestation. Blood samples were collected at 0, 24, and 48 h after tick infestation and evaluated for transcript expression of the CD25, CXCL8, CXCL10, FoxP3, interleukin (IL)-10, and tumor necrosis factor alpha (TNFα) genes. Gene expression of CD25 (6.00, P < 0.01), IL-10 (31.62, P < 0.01), FoxP3 (35.48, P < 0.01), and CXCL10 (3.38, P < 0.05) was altered in the resistant group at 48 h compared with samples collected before infestation. In the susceptible group, CXCL8 (-2.02, P < 0.05) and CXCL10 (2.20, P < 0.05) showed altered expression 24 h after infestation. CXCL8 (-5.78, P < 0.05) also showed altered expression at 48 h after infestation when compared with samples collected before infestation. We detected a correlation between T γδ cell activity and the immunological mechanisms that result in a higher resistance to R. microplus in cattle.

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Section: Experimental Animalsmentioning

confidence: 99%

Expression of immune response genes in peripheral blood of cattle infested with Rhipicephalus microplus

Domingues¹,

Wohlres-Viana²,

Reis³

et al. 2014

Genet. Mol. Res.

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“…And those animals with shorter hairs tend to have lower tick counts compared to those with longer hairs, since long hairs create favourable conditions for tick survival (Taylor et al, 1995;Marufa et al, 2011). Moreover, longer coat hairs may protect ticks from the animal's self-grooming that enables them to remove ticks attached to the coat (Machado et al, 2010). B. indicus were reported to be more innately resistant to B. microplus infestation (Wikel and Whelen, 1986).…”

Section: Discussionmentioning

confidence: 99%

Tick resistance of two breeds of cattle in Wolaita Zone, Southern Ethiopia

Sheferaw¹

2017

J. Vet. Med. Anim. Health

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The objective of this study was to evaluate total tick burden and resistance differences of local indigenous breeds and Holstein-crosses (50%). Longitudinal study method was employed to assess the mean monthly half-body regions of total tick burdens. The mean monthly half body regions of total tick count on local indigenous cattle and Holstein-crosses (50%) were 75.2 and 201.7, respectively. The monthly mean half-body region of total tick count on the Holstein-crosses (50%) was significantly (p<0.05) higher than that of the indigenous breed throughout the study months. From 4425 collected adult ticks, Boophilus decoloratus (47.50%), Amblyomma gemma (21.06%), Amblyomma variegatum (18.31%), Amblyomma cohaerens (4.97%), Amblyomma lepidum (3.75%), Rhipicephalus evertsi evertsi (2.87%), Rhipicephalus muhsamae (0.79%) and Rhipicephalus guilhoni (0.75%) were the tick species identified in descending order. Among the tick species identified, seasonal variation was observed in four species, namely: A. variegatum, A. gemma, A. lepidum and R. evertsi evertsi. Animal health extension especially on tick control strategy should be in place in order to improve animal productivity.

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“…No obstante, la lluvia es importante para la taurus breeds, which show greater granulocytic reaction to tick infestations (15), making the Lucerna animals susceptible to this ectoparasite. Likewise, six genes have been identified that provide tick resistance to Gyr x Holstein cattle and are able to offer protection in different seasons (16). Therefore, the animal genetic component affects the impact of tick infestations in a herd, having been reported that Bos taurus cattle and their crosses are less tolerant of ticks and require more intense and costly control programs than Bos indicus cattle (17).…”

Section: Relación Entre Algunos Factores Abióticos Y La Carga Parasitmentioning

confidence: 99%

Tick loads in Bos taurus cattle grazing in two contrasting production systems

Rosales

P³

2016

Rev MVZ Córdoba

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Objectives. To relate the effect of biotic and abiotic factors on Rhipicephalus (Boophilus) microplus tick loads on cows grazing either in intensive silvopastoral systems (ISS) (Lucerna) or in grass pastures associated with sugarcane plantations (La Isabela). Materials and methods. Tick counts were performed on 27 Lucerne breed animals that were in different physiological states, six of which were grazing on forage grass paddocks associated with commercial sugarcane plantations and the remaining animals grazed in an ISS based on Leucaena leucocephala and Cynodon plectostachyus. The tick counts were made every 15 days. The data of temperature, humidity, and radiation were taken from a weather station that was inside the ISS. Results. There was a weak relationship between saturation deficit and tick load (R 2 =0.34) and another between UV radiation and tick load (R 2 =0.205) for animals grazing in ISS. There were differences in tick counts when comparing animals of similar productivity from both systems evaluated: in La Isabela (sugarcane grass paddocks) average counts were 311 ticks perceptible to the touch (TPT) and in Lucerna (ISS farm) average counts were 206 TPT (p= 0.02). Additionally, there were greater tick counts in high productivity cows compared to low productivity cows. Conclusions. The abiotic and biotic factors of the ecosystem and animal productivity can affect the TPT counts. In ISS systems, tick counts can be lower than those observed in monoculture grazing systems.Key words: Ectoparasites, microclimate, radiation, saturation deficit (Source: CAB). RESUMENObjetivos. Relacionar el efecto de algunos factores bioticos y abioticos sobre las cargas de la garrapata Rhipicephalus (Boophilus) microplus en hembras bovinas que pastorean en sistemas silvopastoriles intensivos (SSPi)(Lucerna) y en monocultivos asociados a cañaduzales (La Isabela). Materiales y métodos. Se realizaron conteos en 27 animales de raza Lucerna en diferentes estados fisiológicos, seis de los cuales se encontraban pastoreando en lotes de gramíneas forrajeras asociados con plantaciones de caña comerciales y los animales restantes pastoreaban en SSPi basados en Leucaena leucocephala y Cynodon plectostachyus. El conteo de garrapatas se efectuó cada 15 días. Los datos de temperatura, humedad y radiación se tomaron de una estación meteorológica que se encontraba en el interior del SSPi. Resultados. Se encontró una relación débil entre el déficit de saturación y los conteos de garrapatas (R 2 =0.34) y entre la radiación UV y los conteos de garrapatas (R 2 =0.205) Rev.MVZ Córdoba 21(2):5404-5415, 2016. ISSN: 0122-0268 ORIGINAL 5405 para los bovinos pastoreando en SSPi. Hubo diferencia entre los conteos en animales con similar productividad en ambos sistemas evaluados; siendo el promedio total de garrapatas perceptibles al tacto (GPT) de 311 para La Isabela y de 206 GPT para Lucerna (p=0.02). Hubo mayor número de GPT en hembras con mayor productividad en comparación con las de baja productividad (p<0.05). Conclusiones. Los factores b...

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Genome wide scan for quantitative trait loci affecting tick resistance in cattle (Bos taurus × Bos indicus)

Cited by 56 publications

References 40 publications

Expression of immune response genes in peripheral blood of cattle infested with Rhipicephalus microplus

Expression of immune response genes in peripheral blood of cattle infested with Rhipicephalus microplus

Tick resistance of two breeds of cattle in Wolaita Zone, Southern Ethiopia

Tick loads in Bos taurus cattle grazing in two contrasting production systems

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