Genome-wide association study revealed the genomic regions associated with skin pigmentation in an Ogye x White Leghorn F2 chicken population

Cha, Jihye; Jin, Daehyeok; Kim, Jaehwan; Kim, Seung-Chang; Lim, Jin A; Chai, Han-Ha; Jung, Seul a; Lee, Jun Heon; Lee, Seung Hwan

doi:10.1016/j.psj.2023.102720

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2024

Publication Types

Select...

Article1

Preprint1

Relationship

Self Cite0

Independent2

Authors

Journals

Cited by 2 publications

References 50 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Genomic insights into shank and eggshell color in Italian local chickens

Perini,

Cendron,

Lasagna

et al. 2024

Poultry Science

View full text Add to dashboard Cite

Genomic insights into shank and eggshell color in Italian local chickens

Perini,

Cendron,

Lasagna

et al. 2024

Poultry Science

View full text Add to dashboard Cite

What is the correct genomic structure of the complex chromosomal rearrangement at theFmlocus in Silkie chicken?

Sharma,

Vijay

2024

Preprint

View full text Add to dashboard Cite

The availability of high-quality chromosome-level genome assemblies of an increasing number of avian species holds significant promise for addressing longstanding questions in bird evolution and biology. In a recent issue of Communications Biology, Zhu, F., Yin, ZT., Zhao, QS. et al. ( ZYZSJ) presented a chromosome-level assembly for the Silkie chicken using a multi-platform high-coverage dataset to obtain accurate and complete sequences spanning the chicken genome. A key finding from their genomic analysis is the reconstruction of the structure of the complex rearrangement at the Fm locus, the primary genetic change underlying the rare and conspicuous dermal hyperpigmentation phenotype generally called Fibromelanosis. However, in contrast to their identification of the *Fm_1 scenario (which the authors refer to as FM2) as the correct arrangement at the Fm locus, several previously published studies claim that *Fm_2 is the valid scenario. Our re-analysis of ZYZSJ's new genome assembly (CAU_Silkie) demonstrates that *Fm_2 is indeed the correct scenario, and the *Fm_1 scenario favoured by ZYZSJ results from an assembly error caused by mosaic haplotypes generated during the de novo assembly step. We recommend that genome projects perform post-assembly validation and correction to safeguard biological interpretations from the impact of assembly artefacts.

show abstract

Genome-wide association study revealed the genomic regions associated with skin pigmentation in an Ogye x White Leghorn F2 chicken population

Cited by 2 publications

References 50 publications

Genomic insights into shank and eggshell color in Italian local chickens

Genomic insights into shank and eggshell color in Italian local chickens

What is the correct genomic structure of the complex chromosomal rearrangement at theFmlocus in Silkie chicken?

Contact Info

Product

Resources

About