Genome‐Wide Association Study of Cardiovascular Resilience Identifies Protective Variation in the
CETP
Gene
Chenglong Yu,
Andrew Bakshi,
Gerald F. Watts
et al.
Abstract:Background
The risk of atherosclerotic cardiovascular disease (ASCVD) increases sharply with age. Some older individuals, however, remain unaffected despite high predicted risk. These individuals may carry cardioprotective genetic variants that contribute to resilience. Our aim was to assess whether asymptomatic older individuals without prevalent ASCVD carry cardioprotective genetic variants that contribute to ASCVD resilience.
Methods and Results
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