Genome-wide analysis of mRNA decay in Arabidopsis shoot and root reveals the importance of co-translational mRNA decay in the general mRNA turnover
Marie-Christine Carpentier,
Anne-Elodie Receveur,
Alexandre Boubegtitene
et al.
Abstract:Until recently, the general 5′-3′ mRNA decay was placed in the cytosol after the mRNA was released from ribosomes. However, the discovery of an additional 5′ to 3′ pathway, the Co-Translational mRNA Decay (CTRD), changed this paradigm. Up to date, defining the real contribution of CTRD in the general mRNA turnover has been hardly possible as the enzyme involved in this pathway is also involved in cytosolic decay. Here we overcame this obstacle and created an Arabidopsis line specifically impaired for CTRD call… Show more
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