Genome Sequencing is Critical for Forecasting Outcomes following Congenital Cardiac Surgery
W. Scott Watkins,
E. Javier Hernandez,
Thomas A. Miller
et al.
Abstract:While genome sequencing has transformed medicine by elucidating the genetic underpinnings of both rare and common complex disorders, its utility to predict clinical outcomes remains understudied. Here, we used artificial intelligence (AI) technologies to explore the predictive value of genome sequencing in forecasting clinical outcomes following surgery for congenital heart defects (CHD). We report results for a cohort of 2,253 CHD patients from the Pediatric Cardiac Genomics Consortium with a broad range of c… Show more
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