Genome sequence of enterohaemorrhagic Escherichia coli O157:H7

Perna, Nicole T.; Plunkett, Guy; Burland, Valerie; Mau, Bob; Glasner, Jeremy D.; Rose, Debra J.; Mayhew, George F.; Evans, Peter; Gregor, J. W.; Kirkpatrick, Heather; Pósfai, György; Hackett, Jeremiah D.; Klink, Sara A.; Boutin, Adam T.; Shao, Ying; Miller, L. L.; Grotbeck, Erik J.; Davis, N. Wayne; Lim, Alex; Dimalanta, Eileen T.; Potamousis, Konstantinos; Apodaca, Jennifer; Anantharaman, Thomas; Lin, Jun-Hsiang; Yen, Galex; Schwartz, David C.; Welch, Rodney A.; Blattner, Frederick R.

doi:10.1038/35054089

Cited by 1,858 publications

(1,692 citation statements)

References 29 publications

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“…Over the past few years, an increasing number of microbial genomes have been sequenced and compared, allowing for the estimation of the frequencies of mutations influencing their genomic structures [118,136]. By quantifying these differences, it has been observed that considerable genomic variability is found both in Escherichia coli and Salmonella enterica [48,109].…”

Section: Source Of Emergence: Microbial Genome Evolutionmentioning

confidence: 99%

Emergence of Salmonella epidemics: The problems related to Salmonella enterica serotyp Enteritidis and multiple antibiotic resistance in other major serotypes

Cloeckaert²,

2005

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-Two major changes in the epidemiology of salmonellosis occurred in the second half of the 20th century: the emergence of food-borne human infections caused by S. Enteritidis and by multiple-antibiotic resistant strains of Salmonella. This review updates information on the S. Enteritidis pandemic and focuses on the emergence of Salmonella, carrying the SGI1 antibiotic resistance gene cluster, resistant to extended-spectrum cephalosporins, or resistant to fluoroquinolones. The factors responsible for the emergence of these Salmonella strains could be either of human origin or related to bacterial genome evolution. However, our increasing understanding of the molecular fluidity of the genome shows that any attempt to counteract bacteria results in further bacterial evolution or adaptation of other bacteria to take place in the new free ecological niche. In these conditions, we can ask who is faster: humans who want to eliminate bacterial pathogens or bacteria that continuously evolve to gain new niches.

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Section: Source Of Emergence: Microbial Genome Evolutionmentioning

confidence: 99%

Emergence of Salmonella epidemics: The problems related to Salmonella enterica serotyp Enteritidis and multiple antibiotic resistance in other major serotypes

Cloeckaert²,

2005

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“…E. coli EDL933 was obtained from F. Blattner (Laboratory of Genetics, University of Wisconsin-Madison) [11]. LuriaBertani (LB) broth was used for culture and plaque assay.…”

Section: Bacterial Strainsmentioning

confidence: 99%

Seasonal change and fate of coliphages infected to Escherichia coli O157:H7 in a wastewater treatment plant

et al. 2003

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Seasonal change of virulent phage infected to two E. coli O157:H7 strains (O:157-phage) in the influent of a domestic wastewater treatment plant in the central part of Japan and fate of O:157-phage in the plant were monitored almost monthly from March 2001 to February 2002. Coliphage infected to nonpathogenic E. coli O157:H7 ATCC43888 (43888-phage) was detected for 1 year. On the other hand, phage infected to pathogenic E. coli O157:H7 EDL933 (EDL-phage) was detected intermittently. Concentration of EDL-phage was almost one-tenth of that of 43888-phage. The progressive decrease in phage concentration with the treatment steps was observed. No phage was detected in the supernatant from the secondary settling tank and effluent. PCR amplification of the Stx 2 gene that encodes Shiga toxin (Stx) was observed when O:157-phage concentration in the influent was high Â 10 3 PFU/ml order. Concentration and percentage of suspended O:157-phage decreased with the progress of the wastewater treatment. 933W phage, which encodes Stx 2 gene, was more fragile and sensitive to chlorination than T4 phage. However, addition of 0.02 mg/l chlorine, in conformance with the required concentration of the plant, did not affect the viability of T4 and 933W phages. On the other hand, 1 mg/l chlorine inactivated the 933W phage significantly. r

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“…The occurrence of tandem termination codons at the ends of genes in two published E. coli genomes, E. coli K-12 strain MG1655 [15] and E. coli O157:H7 strain EDL933 [16], was determined using the Transterm database [14] and a signal counting program (count_signalx).…”

Section: Media and Bacterial Strainsmentioning

confidence: 99%

Tandem termination signals: myth or reality?

et al. 2002

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In two Escherichia coli genomes, laboratory strain K-12 and pathological strain O157 :H7, tandem termination codons as a group are slightly over-represented as termination signals. Individually however, they span the range of representations, over, as expected, or under, in one or both of the strains. In vivo, tandem termination codons do not make more efficient signals. The second codon can act as a backstop where readthrough of the first has occurred, but not at the expected efficiency. UGAUGA remains an enigma, highly over-represented, but with the second UGA a relatively inefficient back up stop codon. ß 2002 Federation of European Biochemical Societies. Published by Elsevier Science B.V. All rights reserved.

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Genome sequence of enterohaemorrhagic Escherichia coli O157:H7

Cited by 1,858 publications

References 29 publications

Emergence of Salmonella epidemics: The problems related to Salmonella enterica serotyp Enteritidis and multiple antibiotic resistance in other major serotypes

Emergence of Salmonella epidemics: The problems related to Salmonella enterica serotyp Enteritidis and multiple antibiotic resistance in other major serotypes

Seasonal change and fate of coliphages infected to Escherichia coli O157:H7 in a wastewater treatment plant

Tandem termination signals: myth or reality?

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