Genome Sequence of Canine Polyomavirus in Respiratory Secretions of Dogs with Pneumonia of Unknown Etiology

Abstract

We report here the first canine polyomavirus genome, identified by metagenomics in respiratory secretions of two dogs with severe pneumonia, which tested negative for all canine respiratory pathogens except Mycoplasma cynos. The isolate, Canis familiaris polyomavirus 1 (DogPyV-1), is a beta polyomavirus whose closest known LT antigen relatives are primate polyomaviruses.

Merkel Cell Polyomavirus and Merkel Cell Carcinoma

“…Cases of MCC has been described in other mammals, including cat, dog and steer [ 273 , 274 , 275 , 276 , 277 , 278 ]. It is not known whether a polyomavirus might be involved in these MCC, but bovine and canine polyomaviruses have been described [ 279 , 280 ], while LiPyV, originally isolated from human skin [ 281 ], was detected in feces of cats [ 282 ]. However, the sT and LT of bovine PyV, dog PyV and LiPyV share <50% homology with the corresponding proteins of MCPyV.…”