Genome Response of Model Invertebrates and Vertebrates Species to Stress Agents in the Environment

Michailova, Paraskeva; Atanasov, Nasko; Ilkova, Julia; Chassovnikarova, T.; Duran, Mustafa; Karadurmuş, Erdal

doi:10.1080/13102818.2010.10817870

Cited by 3 publications

(3 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The important nuclear structures BRs and NOR were very sensitive to stress agents in the environment. The activity of these structures significantly decreased in most of the populations of the species studied (Michailova et al 1998(Michailova et al a, 2010Ilkova 2004 to levels lower than those they showed in larvae from unpolluted sediment (Kiknadze 1978). For instance, in C. riparius from Pancharevo (Bulgaria) the normal high level of activity of BRc and BRb occurred in less than 10% of the examined cells, while the intermediate or depressed levels of activity were observed in more than 86% of the cells (Petrova et al 2004).…”

Section: Functional Alterationsmentioning

confidence: 75%

Polytene chromosomes of Chironomidae (Diptera) as a bioassay of trace-metal-induced genome instability

2012

View full text Add to dashboard Cite

chromosomes of Chironomidae (Diptera) as a bioassay of tracemetal-induced genome instability. Fauna norvegica 31: 227-234. Chironomids are a ubiquitous group of aquatic insects that are very sensitive to environmental stress. Due to the presence of polytene ('giant') salivary gland chromosomes, it is possible to define the genome response of several Chironomid species to various stress agents. The aim of this study was to assess the genotoxic changes in populations of widely distributed chironomid species from aquatic basins in Bulgaria, Italy, Russia, U.K. and Poland, which were exposed to high concentrations of trace metals. We analyzed the structural and functional alterations of polytene chromosomes of the salivary glands of larvae belonging to three different cytocomplexes of the genus Chironomus ("thummi", "lacunarius", "pseudothummi"), and genera Glyptotendipes and Kiefferulus. Somatic structural chromosome rearrangements (para-and pericentric heterozygous inversions, deletions, deficiencies and amplifications) were used to estimate a Somatic index (S) for each population. The highest S indexes were detected in Chironomus riparius populations from locations with high concentrations of trace metals in the sediment. Each species showed specific genome responses to stress agents which we discussed in the light of the specific DNA structures and cytogenetic characteristics of the species. In larvae from polluted sediments two key structures of the salivary gland chromosomes (Balbiani Rings and Nucleolar Organizer) sharply reduced their activity to levels below those observed under non-polluted conditions. It is concluded that polytene chromosomes can be used as tools for evaluating the genotoxicity of the aquatic environment. Structural and functional chromosome alterations provide cost-effective early-warning signals of genotoxic concentrations of environmental pollutants.

show abstract

Section: Functional Alterationsmentioning

confidence: 75%

Polytene chromosomes of Chironomidae (Diptera) as a bioassay of trace-metal-induced genome instability

2012

View full text Add to dashboard Cite

show abstract

“…Comprehensive monitoring of animals living in contaminated areas, that can accumulate the pollutants in their tissues, can provide better information concerning the spatial or temporal changes of the environmental pollution in the ecosystems. These organisms can be used as bioindicators of environmental pollution (Michailova et al 2010 ; Gall et al 2015 ). For an estimation of the RE accumulation in animal organisms, various species have already been tested, comprising i.a.…”

Section: Introductionmentioning

confidence: 99%

The oral bioavailability of soil-borne risk elements for small terrestrial mammals: Microtus arvalis (Pallas, 1778) and Apodemus sylvaticus L. and its implication in environmental studies

Čadková

Vořechovská

Javorská

et al. 2023

Environ Sci Pollut Res

View full text Add to dashboard Cite

The aims of this study were (i) to specify real risk elemetnt (RE) uptake by wild terresrial mammals (A. sylvaticus and M. arvalis), (ii) to describe RE distribution in critical organs such as the liver and kidney, and (iii) to determine potencial differences in RE toxicokinetics with regards to individual species or sex. Three groups of experimental animals were fed diets amended with soil and green biomass of hyperaccumulator Arabidopsis halleri with different RE levels. The contents of As, Cd, and Pb in the liver and kidneys of the animals reflected the element contents in the diet. Higher Cd and Pb accumulation ability was observed in A. sylvaticus compared to M. arvalis tissues, and an opposite pattern was recorded for As. Zn contents in tissues of both species remained unchanged, and total contents of Zn in the exposed animals even tended to decrease compared to the controls. Results of this study indicate a generally similar response of both species to elevated RE contents in the diet, confirming these wild rodents as suitable models for RE biomonitoring in ecosystems. However, our data highlights some distinction in As toxicokinetics in wood mice compared to that of field voles and a significantly higher accumulation of Pb and Cd in females. Therefore, factors of species and sex should not be overlooked if relevant data are to be obtained in environmental studies conducted on small terrestrial rodents.

show abstract

“…Comprehensive monitoring of animals living in contaminated areas, that can accumulate the pollutants in their tissues, can provide better information concerning the spatial or temporal changes of the environmental pollution in the ecosystems. These organisms can be used as bioindicators of environmental pollution (Michailova et al 2010; Gall et al 2015). For an estimation of the RE accumulation in animal organisms, various species have already been tested, comprising i.a.…”

Section: Introductionmentioning

confidence: 99%

The oral bioavailability of soil-borne risk elements for small terrestrial mammals: Microtus arvalis (Pallas, 1778) and Apodemus sylvaticus L. and its implication in environmental studies

Čadková

Vořechovská

Javorská

et al. 2022

Preprint

View full text Add to dashboard Cite

The aims of this study were: i) to specify real risk elemetnt (RE) uptake by wild terresrrial mammals (A. sylvaticus and M. arvalis), ii) to describe RE distribution in critical organs such as liver and kidney, and iii) to determine potencial differences in RE toxicokinetics with regards to individual species or sex. Three groups of experimental animals were fed diets amended with soil and green biomass of hyperaccumulator Arabidopsis halleri with different RE levels. The contents of As, Cd, and Pb in the liver and kidneys of the animals reflected the element contents in the diet. Higher Cd and Pb accumulation ability was observed in A. sylvaticus compared to M. arvalis tissues, and an opposite pattern was recorded for As. Zn contents in tissues of both species remained unchanged, and total contents of Zn in the exposed animals even tended to decrease compared to the controls. Results of this study indicate a generally similar response of both species to elevated RE contents in the diet, confirming these wild rodents as suitable models for RE biomonitoring in ecosystems. However, our data highlights some distinction in As toxicokinetics in wood mice compared to that of field voles and a significantly higher accumulation of Pb and Cd in females. Therefore, factors of species and sex should not be overlooked if relevant data are to be obtained in environmental studies conducted on small terrestrial rodents.

show abstract

Genome Response of Model Invertebrates and Vertebrates Species to Stress Agents in the Environment

Cited by 3 publications

References 24 publications

Polytene chromosomes of Chironomidae (Diptera) as a bioassay of trace-metal-induced genome instability

Polytene chromosomes of Chironomidae (Diptera) as a bioassay of trace-metal-induced genome instability

The oral bioavailability of soil-borne risk elements for small terrestrial mammals: Microtus arvalis (Pallas, 1778) and Apodemus sylvaticus L. and its implication in environmental studies

The oral bioavailability of soil-borne risk elements for small terrestrial mammals: Microtus arvalis (Pallas, 1778) and Apodemus sylvaticus L. and its implication in environmental studies

Contact Info

Product

Resources

About