Genome Editing: Innovation in Molecular Biology

Abstract

Deletion, insertion, or substitution of DNA at a precise location in the genome of an organism is termed as Genome editing. It is usually accomplished in vitro using genetically engineered restriction enzymes endonucleases also called as molecular scissors. There is a numerous way to edit genome using different genome editing systems including CRISPR-Cas9, ZFNs or TALENs. Each of these systems possesses unique properties that are exploited for an organism benefits.