Genome analysis of a new biosurfactants source: The Antarctic bacterium Psychrobacter sp. TAE2020

Riccardi, Christopher; D’Angelo, Caterina; Calvanese, Marzia; Ricciardelli, Annarita; Tutino, Maria; Parrilli, Ermenegilda; Fondi, Marco

doi:10.1016/j.margen.2021.100922

Cited by 8 publications

(11 citation statements)

References 21 publications

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“…Furthermore, the capability of the Antarctic marine bacterium Psycrobacter sp. TAE2020 to produce a multiplicity of bioactive compounds, not only CATASAN, but also surfactants [16] and low molecular molecules active against P. aeruginosa [17], confirms the potential of marine cold-adapted bacteria as a source of novel and interesting bioactivities to be exploited towards the development of innovative approaches for the prevention and treatment of biofilm-associated infections.…”

Section: Discussionmentioning

confidence: 69%

“…Preliminary data demonstrated that the Antarctic marine bacterium Psychrobacter sp. TAE2020 can secrete molecules endowed with surfactant and emulsifying properties [16] and it is able to interfere virulence of several Pseudomonas aeruginosa clinical isolates [17]. In this paper, we focused our attention on its ability to affect S. epidermidis biofilm formation.…”

Section: Discussionmentioning

confidence: 99%

“…T sp. TAE2020 cell-free supernata strain S. epidermidis RP62A [23 a strong biofilm producer [24, ability of SN_TAE2020 to imp -proteobacterium isolated from an Antarctic coastal seawater sample [16]. This marine bacterium is not only able to produce and secrete surfactants and bioemulsifier [16], but its cell-free supernatant strongly affected some specific virulence features of P. aeruginosa isolates from CF patients [17].…”

Section: Psychrobacter Sp Tae2020 P Against S Epidermidis Biofilmmentioning

confidence: 99%

“…In previous work, it was demonstrated that Psychrobacter sp. TAE2020 cell-free supernatant (SN_TAE2020) has surfactant and emulsifier capability [16].…”

Section: Psychrobacter Sp Tae2020 Supernatant Has a Surfactant And Em...mentioning

confidence: 99%

“…Recently, our interest was ƴ -proteobacterium isolated marine bacterium is not only [16], but its cell-free supernata aeruginosa isolates from CF pat…”

Section: Introductionmentioning

confidence: 99%

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CATASAN Is a New Anti-Biofilm Agent Produced by the Marine Antarctic Bacterium Psychrobacter sp. TAE2020

et al. 2022

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The development of new approaches to prevent microbial surface adhesion and biofilm formation is an emerging need following the growing understanding of the impact of biofilm-related infections on human health. Staphylococcus epidermidis, with its ability to form biofilm and colonize biomaterials, represents the most frequent causative agent involved in infections of medical devices. In the research of new anti-biofilm agents against S. epidermidis biofilm, Antarctic marine bacteria represent an untapped reservoir of biodiversity. In the present study, the attention was focused on Psychrobacter sp. TAE2020, an Antarctic marine bacterium that produces molecules able to impair the initial attachment of S. epidermidis strains to the polystyrene surface. The setup of suitable purification protocols allowed the identification by NMR spectroscopy and LC-MS/MS analysis of a protein–polysaccharide complex named CATASAN. This complex proved to be a very effective anti-biofilm agent. Indeed, it not only interferes with cell surface attachment, but also prevents biofilm formation and affects the mature biofilm matrix structure of S. epidermidis. Moreover, CATASAN is endowed with a good emulsification activity in a wide range of pH and temperature. Therefore, its use can be easily extended to different biotechnological applications.

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Section: Discussionmentioning

confidence: 69%

Section: Discussionmentioning

confidence: 99%

Section: Psychrobacter Sp Tae2020 P Against S Epidermidis Biofilmmentioning

confidence: 99%

“…In previous work, it was demonstrated that Psychrobacter sp. TAE2020 cell-free supernatant (SN_TAE2020) has surfactant and emulsifier capability [16].…”

Section: Psychrobacter Sp Tae2020 Supernatant Has a Surfactant And Em...mentioning

confidence: 99%

“…Recently, our interest was ƴ -proteobacterium isolated marine bacterium is not only [16], but its cell-free supernata aeruginosa isolates from CF pat…”

Section: Introductionmentioning

confidence: 99%

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