Genitourinary tuberculosis

Simon, Harvey B; Weinstein, Allan J.; Pasternak, Mark S.; Swartz, Morton N.; Kunz, Lawrence J.

doi:10.1016/0002-9343(77)90279-0

Cited by 201 publications

(44 citation statements)

References 33 publications

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“…These features were absent in this patient. Simon et al [6] found that 95% of 78 patients with genitourinary tract tuberculosis had a positive puri fied protein derivative skin test. Therefore, renal tuber culosis is an unlikely cause of this woman's renal insuffi ciency.…”

Section: Clinical Discussionmentioning

confidence: 99%

A19-Year-Old Female with Fever, Acroparesthesia, and Progressive Deterioration of Renal Function

El-Shahawy¹,

Mesa²,

Koss³

et al. 1996

Am J Nephrol

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Section: Clinical Discussionmentioning

confidence: 99%

A19-Year-Old Female with Fever, Acroparesthesia, and Progressive Deterioration of Renal Function

El-Shahawy¹,

Mesa²,

Koss³

et al. 1996

Am J Nephrol

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“…4,5 Renal colic is present in less than 10% of patients and is secondary to the passage of caseous material, necrotic renal papillary tissue, clots or stones. 1,6 Constitutional symptoms are unusual and found in less that 20% of GU TB patients. 6 The physical exam is usually unremarkable since signs typically develop later in the disease process.…”

Section: Discussionmentioning

confidence: 99%

“…1,6 Constitutional symptoms are unusual and found in less that 20% of GU TB patients. 6 The physical exam is usually unremarkable since signs typically develop later in the disease process. 7 The diagnosis of GU TB should be considered with the findings of an abnormal urinalysis showing sterile pyuria and/or hematuria, which are present in more than 90% of patients.…”

Section: Discussionmentioning

confidence: 99%

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Genitourinary tuberculosis masquerading as a ureteral calculus

Wong

Hoag

Jones

et al. 2013

CUAJ

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The genitourinary tract is a common extrapulmonary site of tuberculosis infection, yet remains a rare clinical entity in North America. We report the case of a 37-year-old man who presented for extracorporeal shock wave lithotripsy for a suspected ureteral stone on imaging. Further workup confirmed a diagnosis of genitourinary tuberculosis. Medical management was undertaken and, ultimately, nephrectomy performed. This case highlights the importance of maintaining a high index of clinical suspicion for genitourinary tuberculosis. Case reportWe report the case of an otherwise healthy 37-year-old male that was referred for extracorporeal shock wave lithotripsy (ESWL) of a presumed left ureteric stone. The patient reported a 2-month history of left flank pain and 5 months of intermittent hematuria. He also reported several months of feeling unwell with occasional fever. The patient was an immigrant from the Philippines, who works as a prison guard in Canada. Physical examination was unremarkable. A kidney, ureter, bladder (KUB) radiography pre-ESWL revealed a 5 × 4-mm oval calcified density within the left hemipelvis that was presumed to represent a ureteral calculus (Fig. 1). Based on history and imaging review, non-contrast and subsequently contrast-enhanced abdominal/pelvis computed tomography (CT) scan were obtained to further workup the etiology of the calcification. These studies demonstrated left hydroureteronephrosis, with renal parenchymal and calyceal calcifications, but no ureteric calculus (Fig. 2). There were innumerable septated cystic lesions throughout the left renal parenchyma that was suspicious for a chronic infection, such as genitourinary (GU) tuberculosis (TB).Urinalysis demonstrated hematuria with sterile pyuria. The patient underwent full evaluation for a working diagnosis of GU TB; chest X-ray was normal. Sputum acid-fast bacillus (AFB) tests were negative. Urine AFB and polymerase chain reaction (PCR) were positive for TB infection. The patient was subsequently medically treated with TB quadruple therapy: Isoniazid, rifampin, ethambutol and pyrazinamide. Urine culture demonstrated growth of Mycobacterium tuberculosis.Due to the presence of left-sided obstruction, cystoscopy was performed for attempted left ureteric stent insertion. Direct visualization revealed an erythematous and friable bladder mucosa with diffuse bleeding. The left ureteric orifice was unable to be visualized. A left percutaneous nephrostomy tube was placed. Antegrade nephrostogram demonstrated dilatation and distortion of the obstructed collecting system with pan-ureteral strictures (Fig. 3).Due to the extensive involvement of the kidney and ureter, reconstruction of the left-sided collecting system and ureter to alleviate the obstruction was not felt feasible upon consensus review. In the setting of a normal, functioning contralateral kidney on nuclear renogram, opinion favoured delayed laparoscopic nephrectomy. After several months of medical treatment and once the urine culture was negative for TB, the patien...

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“…İmmün sistemi normal kişilerde genitoüriner sistem tüberkülozu primer infeksiyonu takiben 8-39yıl arasında ortaya çıkmaktadır (7). Renal transplantasyon sonrası ise genitoüriner TB ortaya çıkış zamanı en erken altı ay en geç beş yıl olarak bildirilmektedir (8)(9)(10).…”

Section: Discussionunclassified

Genitourinary Tuberculosis after Renal Transplantation

Bal¹,

Uyar²,

Karayaylalı³

2011

Turk Neph Dial Transpl

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ÖZTüberküloz (TB), renal transplantasyon sonrası görülen fırsatçı infeksiyonların başında gelmektedir. Ülkemizin de arasında bulunduğu gelişmekte olan ülkelerde TB insidansı yüksektir. Renal transplant alıcılarında TB riski genel popülasyona göre 20-74 kat artmış bulunmuştur. Renal transplant sonrası oluşan genitoüriner TB vakaları nadirdir. Bu hastalarda, graft rejeksiyonu ve kaybı açısından da artmış bir risk söz konusudur.Bu yazıda, böbrek nakli sonrası gelişmiş bir genitoüriner tüberküloz vakası klinik ve laboratuvar özellikleri ile sunulmuştur. AnAhtAR SÖZCÜkleR: Genitoüriner tüberküloz, Renal transplantasyon ABStRACtTuberculosis (TB) is a major opportunistic infection after renal transplantation. The incidence of TB in the general population is high in developing countries including our country. The risk of TB in renal transplant recipients is reported to be 20-74 times higher than that in the general population. Genitourinary TB that occurs after renal transplantation is uncommon. An increased risk of graft rejection and graft loss has been reported.We present a case of genitourinary tuberculosis after renal transplantation, along with its clinical and laboratory properties.

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Genitourinary tuberculosis

Cited by 201 publications

References 33 publications

A19-Year-Old Female with Fever, Acroparesthesia, and Progressive Deterioration of Renal Function

A19-Year-Old Female with Fever, Acroparesthesia, and Progressive Deterioration of Renal Function

Genitourinary tuberculosis masquerading as a ureteral calculus

Genitourinary Tuberculosis after Renal Transplantation

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