Genital tuberculosis among infertile women and fertility outcome after antitubercular therapy

Kulshrestha, Vidushi; Kriplani, Alka; Agarwal, Nutan; Singh, Urvashi; Rana, Tanu

doi:10.1016/j.ijgo.2010.12.014

Cited by 50 publications

(46 citation statements)

References 19 publications

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“…8 In a study by Kulshrestha et al genital tuberculosis was diagnosed in 60.2% infertility women. 9 probable GTB in 37.4%, and TB-PCR was positive in 41.3% of women. Diagnosing GTB by presence of granulomatous lesions on HPR is difficult due to cyclic shedding of endometrium.…”

Section: Discussionmentioning

confidence: 96%

Genital tuberculosis and infertility

Shende¹,

Valecha²,

Gandhewar³

et al. 2017

Int J Reprod Contracept Obstet Gynecol

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Background: An analytical study to diagnose genital tuberculosis, using various modalities, it`s treatment options and fertility outcomes in infertile labour class women.Methods: A prospective study, where 120 women, presented to hospital due to infertility were subjected to hystero-laparoscopy over 36 months. Endometrium sent for TB-PCR and HPR. Those diagnosed with GTB were given Anti-Tubercular Drugs as per standard regimes and their fertility outcome was studied.Results: Out of 120 women, 32(27%) were diagnosed with GTB using accepted clinical criteria, TB-PCR and endometrial HPR. 30 of these 32 were diagnosed by HLscopic picture (94%) alone, 18 by positive endometrial TB-PCR (58%) and another 3 by HPR (10%). Among 32 women treated, 9(28%) conceived after treatment.Conclusions: High incidence of GTB amongst the labour class warrants strong suspicion and early diagnosis using hystero-laparoscopy and prompt treatment to minimize the short and long-term effects of GTB on fertility.

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Section: Discussionmentioning

confidence: 96%

Genital tuberculosis and infertility

Shende¹,

Valecha²,

Gandhewar³

et al. 2017

Int J Reprod Contracept Obstet Gynecol

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“…In present study PCR was positive among 12% of cases. 8 Author % PCR positive Kulshrestha V 8 60.2% Geetika Goel et al 7 22.2% Mondal SK 3 5.88% Present study 12%…”

Section: Discussionmentioning

confidence: 76%

Study to Find Out the Incidence of Genit Al Tuberculosis as a Cause for Female Infertility in Semi - Urban Population

Parikh¹,

Deshpande²,

Madkar³

et al. 2014

jemds

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“…[22] a study by Vidushi, Alkakriplani and others on genital tuberculosis in 196 cases fertility outcome after anti-tubercular treatment was 31%. [23] V. N. Jindal, S. Verma and Y Bala in their study of 443 cases on fertility outcomes following anti-tubercular treatment showed overall pregnancy rate of 59.8%. [24] In our study treatment to all affected individual was given.…”

Section: Discussionmentioning

confidence: 96%

Study of Genital Tuberculosis in Infertile Women

Ohri¹,

Patil²,

Patil³

et al. 2016

jemds

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AIMTo determine the incidence of female Genital Tuberculosis (GTB) and to analyse clinicopathological features for GTB and comparison of Polymerase Chain Reaction (PCR), Acid Fast Bacillus (AFB) staining and Histopathology (HPR). STUDY SETTINGA prospective study conducted on 50 infertile patients in the Department of Obstetrics and Gynaecology at Krishna Hospital, Karad, for a period of 2 years between December 2013 and December 2015. METHODSPatients were investigated for the presence of Mycobacterium Tuberculosis (MTB) on samples collected by endometrial curettage by PCR, AFB and HPR. Additional tests like Hysterosalpingography (HSG) Laparoscopic chromopertubation and hysteroscopy were performed if not done earlier. RESULTPCR demonstrated MTB DNA in 9 patients, and 2 were positive with AFB and HPR. Within positive patients HSG findings were suggestive of TB in 3 cases and laparoscopy in 5 cases and hysteroscopy in 4 cases. Two MTB PCR positive patients conceived spontaneously after 6 months of anti-tubercular treatment.

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Genital tuberculosis among infertile women and fertility outcome after antitubercular therapy

Abstract: No single test can detect all instances of GTB. A combination of tests is needed to increase the detection rate. Treatment given solely on the basis of a positive PCR result can result in conception.

Cited by 50 publications

References 19 publications

Genital tuberculosis and infertility

Genital tuberculosis and infertility

Study to Find Out the Incidence of Genit Al Tuberculosis as a Cause for Female Infertility in Semi - Urban Population

Study of Genital Tuberculosis in Infertile Women

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