Genital Tuberculid in a Female Child: A New Entity (Childhood Vulval Tuberculid)

Pandhi, Depika; Mehta, Shilpa; Singal, Archana

doi:10.1111/j.1525-1470.2007.00530.x

Cited by 17 publications

(6 citation statements)

References 10 publications

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“…LS confined to the vulva, associated with cervical and inguinal tubercular lymphandenitis, has been reported in an 11-year-old girl. [29] Phlyctenular keratoconjunctivitis as a manifestation of immunological response to suspected TB antigen has also been reported with LS in a child with SFD/LV. [30] Histology from lesions shows superficial perifollicular epithelioid granulomas without any caseation.…”

Section: Tubercular Gummamentioning

confidence: 96%

Cutaneous tuberculosis in children: The Indian perspective

Singal¹,

Sonthalia²

2010

Indian J Dermatol Venereol Leprol

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Cutaneous tuberculosis continues to be a significant medical problem even with the advent of highly effective antituberculous drugs. It constitutes about 1.5% of all extra pulmonary tuberculosis. The prevalence in children varies from 18 to 54% in India. There is no gender predilection and the infection occurs with increased frequency in 10-14 year age group. Intrafamilial source of TB has been observed very frequently. A concomitant TB lymphadenitis is most common while involvement of other systemic organs like lung, bone and abdomen has also been observed. Protective efficacy of BCG is debatable and not yet fully defined. Of all the clinical types, scrofuloderma (SFD) is the most commonly encountered variant followed by lupus vulgaris (LV) and tuberculosis verrucosa cutis (TBVC). Lichen scrofulosorum (LS) is generally found to be associated with systemic TB focus in about 72% of cases. The impact of HIV on childhood cutaneous TB seems to be minimal. Similar to adults, the diagnosis of cutaneous tuberculosis relies mainly on histopathology, culture on LJ medium or radiometric BACTEC 460 TB culture system and PCR. In addition Mantoux positivity and a positive therapeutic trial with anti-tubercular drugs may be a good pointer to tubercular infection. A thorough clinical evaluation and exhaustive investigations to pin-point associated systemic focus is advocated as the latter has an impact on the duration of treatment. Cutaneous TB in children is treated as per the recommendations of therapy for extrapulmonary TB.

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Section: Tubercular Gummamentioning

confidence: 96%

Cutaneous tuberculosis in children: The Indian perspective

Singal¹,

Sonthalia²

2010

Indian J Dermatol Venereol Leprol

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“…The acral extremities and earlobes are the sites of predilection, but localized lesions can occur on the face and buttocks. Isolated childhood vulval papulonecrotic tuberculid (genital tuberculid) has been described (24). Papulonecrotic tuberculids in children have been reported to occur with active pulmonary and lymph node tuberculosis.…”

Section: Papulonecrotic Tuberculidsmentioning

confidence: 99%

Cutaneous Tuberculosis in Children

Sethuraman

Ramesh

2012

Pediatric Dermatology

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Cutaneous tuberculosis is a rare form of extrapulmonary tuberculosis that accounts for 1% to 2% of cases. Childhood skin tuberculosis represents 18% to 82% of all cutaneous tuberculosis cases. Scrofuloderma and lupus vulgaris are the two most common clinical forms in children. An increase in the number of tuberculids, especially lichen scrofulosorum, has been observed in the last several years. Cutaneous tuberculosis in children can be severe and have a protracted course. Multiplicity of lesions and multifocal disseminated involvement in scrofuloderma and lupus vulgaris is common. Scrofuloderma progressing to gummatous lesions (scrofulous gumma) is mostly described in children. Morbidities and deformities are more severe in children.

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“…They are mainly found in abdomen, chest, and back but may affect any area of the skin, including the face, 21 palms, and soles 22 and the external genitalia. 23,24 In rare instances, blistering and reproduction of the lesions at the injection site of Mantoux test, as was the case in our patient, have been described. 18,25 In some cases, as occurred also in our case, the eruption appears after initiation of antituberculous drug treatment, and this event is considered the result of an increase in cell-mediated immune status.…”

Section: Discussionmentioning

confidence: 53%

Lichen Scrofulosorum Mimicking Lichen Planus

Camacho

Pielasinski²,

Revelles³

et al. 2011

The American Journal of Dermatopathology

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Lichen scrofulosorum is the most uncommon clinicopathologic variant of the tuberculids. Usually, the eruption appears in children and adolescents with strong immune sensitivity to Mycobacterium tuberculosis and consists of tiny follicular papules, closely resembling lichen nitidus. We report a case of lichen scrofulosorum in an adult male with active cervical scrofuloderma who developed lesions of lichen scrofulosorum mimicking clinically lichen planus. Histopathologic study demonstrated granulomas around the hair follicles, although acid-fast bacilli stains, immunohistochemical stain for mycobacteria, polymerase chain reaction investigations and cultures failed to demonstrate Mycobacterium tuberculosis in the cutaneous lesions. The most striking features of the reported case were the onset of the eruption in an adult patient and the clinical appearance of the lesions, resembling lichen planus.

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Genital Tuberculid in a Female Child: A New Entity (Childhood Vulval Tuberculid)

Cited by 17 publications

References 10 publications

Cutaneous tuberculosis in children: The Indian perspective

Cutaneous tuberculosis in children: The Indian perspective

Cutaneous Tuberculosis in Children

Lichen Scrofulosorum Mimicking Lichen Planus

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