Genital Herpes: Gynaecological Aspects

Money, Deborah; Steben, Marc; Wong, Thomas; Gruslin, Andrée; Yudin, Mark H.; Cohen, Howard; Boucher, Marc; MacKinnon, Catherine Jane; Paquet, Caroline; Schalkwyk, Julie van

doi:10.1016/s1701-2163(16)32805-5

Cited by 8 publications

(39 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…6 Diagnosis laboratorium sangat dibutuhkan untuk keberhasilan terapi. 20 Setiap wanita hamil yang dicurigai terinfeksi virus herpes harus dikonfirmasi dengan pemeriksaan kultur virus atau serologis untuk menentukan infeksi primer atau rekuren. 12 Disertai edukasi baik terhadap pasien dan pasangannya.…”

Section: Diagnosisunclassified

“…12 Disertai edukasi baik terhadap pasien dan pasangannya. 20 Dua kategori pemeriksaan infeksi HSV: 19 19 Kultur sel virus harus dilakukan pada pasien yang tidak memiliki riwayat infeksi HG. Kedua pemeriksaan ini sangat baik dilakukan saat awal terbentuknya lesi, yaitu pada vesikel, pustul, atau ulkus yang basah.…”

Section: Diagnosisunclassified

“…Kedua pemeriksaan ini sangat baik dilakukan saat awal terbentuknya lesi, yaitu pada vesikel, pustul, atau ulkus yang basah. 19,20 Tes ini tidak dilakukan saat ulkus telah mengering dan telah muncul krusta. 20 Deteksi virus dapat dilakukan di awal penyakit dan keberhasilannya tinggi.…”

Section: Diagnosisunclassified

“…19,20 Tes ini tidak dilakukan saat ulkus telah mengering dan telah muncul krusta. 20 Deteksi virus dapat dilakukan di awal penyakit dan keberhasilannya tinggi. 22 Sensitivitas kultur virus sangat rendah terutama untuk lesi rekuren dan menurun cepat saat lesi menyembuh.…”

Section: Diagnosisunclassified

See 3 more Smart Citations

Tatalaksana Herpes Genitalis pada Kehamilan

Triana

Ayu

Zulfikar

et al. 2020

CDK

View full text Add to dashboard Cite

Herpes simplex virus (HSV) adalah penyebab herpes genitalis (HG). Perubahan imunologi saat kehamilan akan meningkatkan kerentanan terhadap infeksi HSV yang merupakan penyebab morbiditas dan mortalitas ibu dan janin. Pengaruh infeksi ini pada ibu dan janin/neonatus tergantung apakah infeksi primer (inisial) atau rekuren. Penentuan episode infeksi HG penting baik untuk tatalaksana maupun edukasi pasien.Genital herpes is caused by Herpes simplex virus (HSV). Immunologic changes in pregnancy may increase susceptibility to HSV infection as one of the major cause of morbidity and mortality for both mother and fetus. The effect to the mother and fetus/ neonate depends on whether a primary infection (initial) or a recurrent infection. Determination of an episode of genital herpes is important to provide best management and education.

show abstract

Section: Diagnosisunclassified

See 2 more Smart Citations

Tatalaksana Herpes Genitalis pada Kehamilan

Triana

Ayu

Zulfikar

et al. 2020

CDK

View full text Add to dashboard Cite

show abstract

“…It is estimated that there are new cases of genital herpes in Canada per year with approximately new cases each day [1]. The Centers for Disease Control and Prevention (CDC) estimates that at least 45 million Americans, or one in five adolescents and adults, have genital herpes infection.…”

Section: Introductionmentioning

confidence: 99%

Epidemiological Impact of a Genital Herpes Type 2 Vaccine for Young Females

et al. 2012

Self Cite

View full text Add to dashboard Cite

Genital Herpes, which is caused by Herpes Simplex Virus-1 or -2 (HSV-1, -2, predominantly HSV-2) is a sexually transmitted infection (STI) that causes a chronic latent infection with outbreak episodes linked to transmission. Antiviral therapies are effective in reducing viral shedding during these episodes, but are ineffective as a whole since many outbreaks are asymptomatic or have mild symptoms. Thus, the development of a vaccine for genital herpes is needed to control this disease. The question of how to implement such a vaccine program is an important one, and may be similar to the vaccination program for Human Papilloma Virus (HPV) for young females. We have developed a mathematical model to describe the epidemiology of vaccination targeting young females against HSV-2. The model population is delineated with respect to age group, sexual activity and infection status including oral infection of HSV-1, which may affect vaccine efficacy. A threshold parameter , which determines the level of vaccine uptake needed to eradicate HSV-2, is found. Computer simulation shows that an adolescent-only vaccination program may be effective in eliminating HSV-2 disease, however, the success of extinction greatly depends on the level of vaccine uptake, the vaccine efficacy, the age of sexual maturity and safe sex practices. However, the time course of eradication would take many years. We also investigate the prevalence of infection in the total population and in women between 16–30 years of age before and after vaccination has been introduced, and show that the adolescent-only vaccination program can be effective in reducing disease prevalence in these populations depending on the level of vaccine uptake and vaccine efficacy. This will also result in a decrease of maternal-fetal transmission of HSV-2 infection. Another important, if commonsense, conclusion is that vaccination of some females reduces infection in men, which then reduces infection in women.

show abstract

No. 208-Guidelines for the Management of Herpes Simplex Virus in Pregnancy

Money

Steben²

2017

Journal of Obstetrics and Gynaecology Canada

View full text Add to dashboard Cite

Genital Herpes: Gynaecological Aspects

Cited by 8 publications

References 16 publications

Tatalaksana Herpes Genitalis pada Kehamilan

Tatalaksana Herpes Genitalis pada Kehamilan

Epidemiological Impact of a Genital Herpes Type 2 Vaccine for Young Females

No. 208-Guidelines for the Management of Herpes Simplex Virus in Pregnancy

Contact Info

Product

Resources

About