Genital Condylomas in Immunosuppressed Women: A Therapeutic Challenge

Therapy of external anogenital warts and molluscum contagiosum: a literature review

“…Ferenczy (73) recommended that vaginal condylomata were most effective and least painfully treated with intravaginal 5‐FU cream combined with protection of the vulva; flat condylomata are best managed by CO 2 laser therapy; and refractory lesions may benefit from 5‐FU and CO 2 laser therapy. While topical 5‐FU is relatively ineffective against large wart lesions, it has been used successfully in maintenance treatment in immunosuppressed women with lesions of the lower genital tract (75).…”

Successful Treatment of Extensive Condyloma Acuminata of the Inguinal Area and Thigh with Topical Imiquimod Cream

“…They are often pulsatile but rarely ulcerated. An unusual presentation as a hyperkeratotic lesion mimicking a cutaneous horn has been described (4). The size of individual cutaneous metastatic lesions, as reported in the literature, varies greatly from 0.5 to 5.6 cm in diameter although most of the lesions measured 53 cm.…”

New approaches to the understanding of the pathogenesis of human papilloma induced anogenital lesions The role of co‐factors and co‐infection

“…In patients with chronic renal failure and general debilitation due to long-term hemodialysis, a latent HPV infection can be reactivated, leading to dysplasia. Lower genital tract neoplasias have also been reported in 67% of cardiac transplant recipients with previous condylomata [91]. Various HPV types are found in these lesions, but oneogenic HPV predominate, particularly in patients with a high level of immunosuppression [92].…”