Abstract:Numerous teams are trying to find a genetic determination of individuals with high risk of myocardial infarction. Originally more attention was paid to candidate genes of atherosclerosis risk factors -hypercholesterolemia and hypertension. Out of several hundreds of potential genes involved, only effect of polymorphism of apolipoprotein E was reproduced in different settings and populations. Attention was focused to genes involved in monocyte behavior, arterial wall metabolism, and thromboembolic process more … Show more
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