Genetics of cortical development

Bella, Daniela Di; Habibi, Ehsan

doi:10.1016/b978-0-12-818872-9.00108-4

Cited by 1 publication

(1 citation statement)

References 209 publications

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“…Artificial intelligence and all its esoteric offshoots now occupy the Olympus of fashion. Just think of the "neural networks", which have been given this suggestive name simply because they are inspired by the functioning of biological neurons, but they actually have nothing in common with biology [3,4]. To understand the inappropriate and dangerous association, just think of a network of tanks connected by tubes, which could legitimately be called a "urological network", inspired by the functioning of the bladder and urethra.…”

Section: Introductionmentioning

confidence: 99%

Systems Precision Medicine: Putting the Pieces Back Together

Farina

2023

Systems

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Systems precision medicine is an interdisciplinary approach that recognises the complexity of diseases and emphasises the integration of clinical knowledge, multi-omics data, analytical models, and the expertise of physicians and data analysts to personalise the care pathway in complex diseases, such as cancer or diabetes. The aim is to gain a comprehensive understanding of diseases by analysing individual components and identifying relevant aspects for therapy and diagnosis. Key components, their interactions and emerging patterns can be studied using statistical, mathematical and computational tools. The combination of data analysis and clinical evaluation is crucial to effective decision-making, emphasising the need for an integrative approach rather than relying on data alone. Therefore, the crucial point discussed in this paper is that the “computational” part and the “artistic” part (i.e., the physician’s intuition) cannot be separated, and therefore, systems precision medicine can be configured as a collective work of art, involving not only different medical professionals but also, and above all, professional data analysts. The work is “artistic” because data and mathematics alone, without medical knowledge of the context, are not enough. But the work is also “collective” in the sense that it must be the place of cultural integration between the professional intuition of the physician, which cannot be translated into mathematical formulas, and the ability to extract information from multi-omics data of the data analysts, who instead use formal and computational mathematical methods. However, to drive the medical revolution and reassemble a patient’s parts, data analysts need to be involved in the hospital context, and precision medicine physicians should embrace data analytical perspectives. This will require ongoing dialogue, new languages of communication, and education that promotes continuous learning and collaboration between professions, fostering a new level of interdisciplinary collaboration for personalised care.

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Section: Introductionmentioning

confidence: 99%

Systems Precision Medicine: Putting the Pieces Back Together

Farina

2023

Systems

View full text Add to dashboard Cite

show abstract

Genetics of cortical development

Cited by 1 publication

References 209 publications

Systems Precision Medicine: Putting the Pieces Back Together

Systems Precision Medicine: Putting the Pieces Back Together

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