Genetics identifies obesity as a shared risk factor for co-occurring multiple long-term conditions
Ninon Mounier,
Bethany Voller,
Jane AH Masoli
et al.
Abstract:BackgroundMultimorbidity, the co-occurrence of multiple long-term conditions (LTCs), is an increasingly important clinical problem, but often little is known about the underlying causes. Observational studies are highly susceptible to confounding and bias, and patients with multiple LTCs are usually excluded from randomised controlled trials. We investigate the role of a potentially critical multimorbidity risk factor, obesity, as measured by body mass index (BMI), in explaining shared genetics amongst 71 comm… Show more
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