Genetics and the Origins of the British Population

Richards, Martin B.; Capelli, Cristian; Wilson, James F.

doi:10.1002/9780470015902.a0020804

Cited by 3 publications

(2 citation statements)

References 17 publications

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“…For example in 1851, 0.6% of the residents of England and Wales had been born outside the UK, 1.5% in 1901, and 2.6% in 1931, rising to 4.5% in 1961 and to 11.6% in 2010 (there was no British census in 1941). Indeed, genetic analysis suggests that most ancestry in NW Europe is very ancient (McEvoy et al ., ; Novembre et al ., ; Richards et al ., ), although research in this area develops quickly, and the matter is far from settled. Novel increases in the volume of immigration, and in the diversity of sources of immigration, only began in the last few decades of the 20th century and have accelerated since.…”

Section: Data Assumptions and Methodsmentioning

confidence: 99%

New Measures of Population Reproduction for an Era of High Migration

Ediev

Coleman

Scherbov

2013

Population Space and Place

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Migration has become a key factor in the growth and replacement of populations. But demographic tools for its analysis remain simple. This paper is our response to those problems. We propose a set of simple, singlenumber indicators, which summarise the aggregate effect of the major contributing factors to the reproduction of populations. Our estimates imply that the persistence of rates observed since 2004 would lead to robust population growth in the North-Western and Northern economically developed European countries. On the other hand, countries in the East of the EU and Central European countries would face substantial population decline due both to their low fertility and to low or negative net migration. If current inflows and fertility levels persist, then within 50 years, people who migrated after 2004 and their descendants will comprise more than half of the population at childbearing and younger ages in some European countries.

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Section: Data Assumptions and Methodsmentioning

confidence: 99%

New Measures of Population Reproduction for an Era of High Migration

Ediev

Coleman

Scherbov

2013

Population Space and Place

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“…The most striking pattern in Scotland and England is a strong east-to-west differentiation, a palimpsest resulting no doubt from multiple immigrations from the east. 8 Mitochondrial DNA analysis also reveals lower than average diversity in Ireland, but not Britain. 9 Using a data set of 4424 SNPs, we previously confirmed the close genetic relationship between Irish and neighbouring European populations and illustrated the suitability of the HapMap Utah Centre d'Etude du Polymorphisme Humain (CEPH) data set for the design of LD-based genetic mapping studies in the Irish population.…”

Section: Introductionmentioning

confidence: 99%

Population structure and genome-wide patterns of variation in Ireland and Britain

et al. 2010

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Located off the northwestern coast of the European mainland, Britain and Ireland were among the last regions of Europe to be colonized by modern humans after the last glacial maximum. Further, the geographical location of Britain, and in particular of Ireland, is such that the impact of historical migration has been minimal. Genetic diversity studies applying the Y chromosome and mitochondrial systems have indicated reduced diversity and an increased population structure across Britain and Ireland relative to the European mainland. Such characteristics would have implications for genetic mapping studies of complex disease. We set out to further our understanding of the genetic architecture of the region from the perspective of (i) population structure, (ii) linkage disequilibrium (LD), (iii) homozygosity and (iv) haplotype diversity (HD). Analysis was conducted on 3654 individuals from Ireland, Britain (with regional sampling in Scotland), Bulgaria, Portugal, Sweden and the Utah HapMap collection. Our results indicate a subtle but clear genetic structure across Britain and Ireland, although levels of structure were reduced in comparison with average cross-European structure. We observed slightly elevated levels of LD and homozygosity in the Irish population compared with neighbouring European populations. We also report on a cline of HD across Europe with greatest levels in southern populations and lowest levels in Ireland and Scotland. These results are consistent with our understanding of the population history of Europe and promote Ireland and Scotland as relatively homogenous resources for genetic mapping of rare variants.

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Bronze- and Iron-Age Celtic-speakers: what don't we know, what can't we know, and what could we know? Language, genetics and archaeology in the twenty-first century

Sims-Williams

2012

Antiq. J.

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Genetics and the Origins of the British Population

Cited by 3 publications

References 17 publications

New Measures of Population Reproduction for an Era of High Migration

New Measures of Population Reproduction for an Era of High Migration

Population structure and genome-wide patterns of variation in Ireland and Britain

Bronze- and Iron-Age Celtic-speakers: what don't we know, what can't we know, and what could we know? Language, genetics and archaeology in the twenty-first century

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