Genetics and mechanisms of insecticide resistance in Ceratitis capitata and its implications for resistance management

Amat, Ana Guillem

doi:10.20868/upm.thesis.57357

Cited by 1 publication

(4 citation statements)

References 188 publications

(378 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A recent study did not reveal significant levels of resistance of field populations to deltamethrin and spinosad in Greece. 12 However, Guillem-Amat (2019) 18 reported that Mag-netMed traps coated with deltamethrin do not provide a complete control for all Spanish field populations tested. Altogether, IRM strategies aimed to overcoming resistance to lambdacyhalothrin and preventing the development of resistance to spinosad and deltamethrin are required.…”

Section: Discussionmentioning

confidence: 99%

“…The existence of cross‐resistance between lambda‐cyhalothrin and deltamethrin (MO1), as observed for the resistant laboratory strain W‐1Kλ 6 . In this case, the expected mortality for SS individuals would be s ( d ) SS = 0.9, as it was observed that not all the individuals from the susceptible laboratory strain C reach the traps and die 18 . The absence of cross‐resistance between lambda‐cyhalothrin and deltamethrin in field populations (MO2), in which all the genotypes would be expected to be as sensitive as C strain ( s ( d ) SS = s ( d ) RR = s ( d ) SR = 0.9).…”

Section: Methodsmentioning

confidence: 97%

“…18 The absence of cross-resistance between lambda-cyhalothrin and deltamethrin in field populations (MO2), in which all the genotypes would be expected to be as sensitive as C strain (s(d) SS = s(d) RR = s(d) SR = 0.9). The intermediate situation with partial cross-resistance (MO3), in which the average mortality to MagnetMed traps coated with deltamethrin obtained for field populations 18 was assumed for the resistant homozygous (s (d) RR = 0.4), and for the heterozygous it was considered the possibility of being as sensible as the RR (s(d) SR = 0.4; MO3.1), as sensible as the SS (s(d) SR = 0.9; MO3.3), or the mean value between both (s(d) SR = 0.65; MO3.2). For the polygenic model, three equivalent scenarios were considered ( Five different hypothetical settings of fitness cost values (being w XY the fitness cost or selection coefficient of genotype XY) were tested to determine which better fitted the current trends in field resistance development.…”

Section: (B))mentioning

confidence: 99%

“…6 In this case, the expected mortality for SS individuals would be s(d) SS = 0.9, as it was observed that not all the individuals from the susceptible laboratory strain C reach the traps and die. 18 The absence of cross-resistance between lambda-cyhalothrin and deltamethrin in field populations (MO2), in which all the genotypes would be expected to be as sensitive as C strain (s(d) SS = s(d) RR = s(d) SR = 0.9). The intermediate situation with partial cross-resistance (MO3), in which the average mortality to MagnetMed traps coated with deltamethrin obtained for field populations 18 was assumed for the resistant homozygous (s (d) RR = 0.4), and for the heterozygous it was considered the possibility of being as sensible as the RR (s(d) SR = 0.4; MO3.1), as sensible as the SS (s(d) SR = 0.9; MO3.3), or the mean value between both (s(d) SR = 0.65; MO3.2).…”

Section: (B))mentioning

confidence: 99%

See 3 more Smart Citations

Current situation and forecasting of resistance evolution to lambda‐cyhalothrin in Spanish medfly populations

Guillem‐Amat

López‐Errasquín

Castells-Sierra

et al. 2021

Pest Management Science

View full text Add to dashboard Cite

BACKGROUND The control of the Mediterranean fruit fly Ceratitis capitata (Wiedemann) in Spanish field populations mainly relies on the insecticides lambda‐cyhalothrin and spinosad as bait sprays. However, their sustainable used is compromised by the development of lambda‐cyhalothrin resistance and the detection of spinosad resistant alleles. In addition, the use of lure‐and‐kill traps covered with deltamethrin has increased in the last years. It is thus urgent to predict the impact that the combination of both pyrethroids will have in the evolution of lambda‐cyhalothrin resistance and how they could be combined with spinosad so as to establish proper resistance management programs. RESULTS Toxicity bioassays were performed to analyze the current levels of lambda‐cyhalothrin resistance in field populations, proving that it has remained stable in the last decade. An evolutionary model was established to explore the weight of selected parameters in the evolution of lambda‐cyhalothrin resistance in C. capitata and to forecast resistance development under different resistance management scenarios. Our results highlight the importance of fitness cost and inheritance to fit the experimental results. The analyses predicted that the rotation of lambda‐cyhalothrin and spinosad, when deltamethrin traps are also deployed in the field, will slow down the evolution of resistance, especially when cross‐resistance between both pyrethroids is considered. CONCLUSION Lambda‐cyhalothrin resistance has not increased in the last decade, probably due to the alternation of this insecticide with spinosad. Our modelling results indicate that the best option to avoid an increase in lambda‐cyhalothrin resistant alleles, considering that deltamethrin use is growing, would be to continue combining their use with spinosad. © 2021 The Authors. Pest Management Science published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 97%