Genetics and control of avian diseases

Payne, L. N.

doi:10.1080/03079457309353800

Cited by 12 publications

(5 citation statements)

References 37 publications

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“…They may be (1) due to a gene with a pleiotropic action, that is, more than one phenotypic expression, or (2) due to true genetic linkage, that it, the presence of two different genes on the same chromosome (Payne 1973;Hutt, 1958Hutt, , 1974Hutt, , 1975.…”

Section: Discussionmentioning

confidence: 99%

Genetic Markers of Resistance to Leptospirosis in Pigs of the Large White Polish Breed

Przytulski¹,

Porzeczkowska²

1980

Acta Vet. Brno

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Prz y tu lsk i T., D. Por ae czkowska: Genetic Markers of Resistance to Leptospirosis in Pigs of the Large White Polish Breed. Acta vet. Brno, 49, 1980: 237 -244. , Data obtained from 1200 Large White pigs in two farms show that in pigs producing Am BB, Akp AB, Pra AB or BB, Tf AB there is a significantly lower incidence of leptospirosis than in pigs producing Am AB, Akp BB or Be, Pra AA and Tf BB phenotypes. A significantly lower incidence also appears in pigs heterozygous for Hpx as compared to homozygous and a higher incidence in homozygotes Hpx 1-1 as compared to the other homozygous considered together. This result was confirmed by the relationship between these phenotypes and the level of leptospira antibodies as" well as by the effect of selection in relation to polymorphic loci.

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Section: Discussionmentioning

confidence: 99%

Genetic Markers of Resistance to Leptospirosis in Pigs of the Large White Polish Breed

Przytulski¹,

Porzeczkowska²

1980

Acta Vet. Brno

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“…It is greatly influenced by the severity of exposure to the pathogen (virulence, dosage) and environmental stress (Hutt 1958(Hutt , 1974(Hutt , 1975Payne 1973;Bradley and Spooner 1977). In this study determining the type of inheritance of leukaemia resistance was very difficult.…”

Section: Discussionmentioning

confidence: 99%

Genetic Resistance to Leukaemia in Black-and-White Cattle

Przytulski¹,

Bartoszewicz²,

Kamieniecki³

et al. 1981

Acta Vet. Brno

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Przytulski T., B. Bartoszewicz, H. Kamieniecki, A. Kaw~cki, A. Klemke, L. Niemyska, W. Belec: Genetic Resistance to Leukaemia in Black-and-White Cattle. Acta vet. Brno, 50, 1981: 61-66. Data obtained from 1312 Black-and-White cows of 75 bulls from different farms shows that bulls transmitted different levels of resistance or susceptibility to leukaemia to their daughters. It can be used in practice for early elimination of bulls which are genetically predisposed to leukaemia. The h 2 of leukaemia resistance was 0.13. Relationship between blood groups, transferrins, postalbumins, amylase, xCn, cc.,-Cn, {J-Cn (caseins) and {J-Lg phenotypes and leukaemia was also analyzed. In cows secreting xCn AA types there is a significantly lower incidence of leukaemia than in cows producing xCn BB or AB types. The frequency of Y2D'G'1' allele in cows with leukaemia was very high. The differences for the other phenotypes were not significant. Resistance, leukaemia, cattle, polymorphism.Leukaemia is a major animal disease. A significant percentage of domestic and wildlife animal

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“…It is intuitively obvious that most diseases are, at least to some degree, genetically predisposed because most diseases affect only a few species. Furthermore, resistance to some diseases is known to be related to particular genetic loci, e.g., Marek's disease in poultry (Payne, 1973) and many human and mouse diseases (Bach, 1982). Another example of genetically determined disease is internal parasite resistance (e.g., Preston and Allonby, 1978).…”

Section: A Number Of Recent Studies Have Demonstrated That Exogenous mentioning

confidence: 99%

Genetic Engineering of Laboratory and Livestock Mammals

Wagner

Murray

1985

Journal of Animal Science

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Recent advances in recombinant genetics have made possible the transfer of cloned genes from one organism to the genome of another. Research with mice made transgenic by insertion of rat or human genes has provided direct evidence that transferred genes can be incorporated into the germline and expressed in the recipient. Current technology for gene transfer involves microinjection of the recombinant genes into the male pronucleus of the zygote. Resulting transgenic mice, when mated as adults, produced offspring that contained and expressed the transgenes. These observations serve as indications of the possibilities that exist for genetic engineering in livestock species. Although there are some technical problems to be overcome before livestock embryos can be genetically altered by these means, the genes for producing growth hormone transgenic livestock are currently available, and research groups are working toward this objective. In addition to this work with growth hormone genes, there are many other potential applications for genetic engineering livestock to produce more highly efficient production; however, there is considerable research to be done before the full potential of this technology can be achieved. It will be necessary to identify other genes that have potential for improving the production efficiency of livestock, and it will be necessary to gain a more complete understanding of the developmental and molecular biology of livestock. The potential impact of this technology in farm animal production is enormous, but, in the short term, it will be a costly endeavor.

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Genetics and control of avian diseases

Cited by 12 publications

References 37 publications

Genetic Markers of Resistance to Leptospirosis in Pigs of the Large White Polish Breed

Genetic Markers of Resistance to Leptospirosis in Pigs of the Large White Polish Breed

Genetic Resistance to Leukaemia in Black-and-White Cattle

Genetic Engineering of Laboratory and Livestock Mammals

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