Genetics and chemistry of bacterial flagella.

Phase variation of the H antigen in Escherichia coli strain Bi7327-41, the standard strain for Escherichia coli flagellar antigen H3

“…Thus, all these data showed that E. coli strain Bi7327-41 is really diphasic and that the flagellar antigen specificities and their variation in this strain are controlled by a special genetic system of functionally connected genes which resembles that known in Salmonella [6]. There are two genes, H1 and H2, specifying phase-1 and phase-2 type flagellins, respectively, in Salmonella [7,8].…”

Biochemical similarity among serologically distinct flagellins of Campylobacter jejuni

“…Met-Arg-Ile-Asn-His-Asn-Ile-Ala-Ala-Leu-Asn-Thr-Leu-Asn during acid hydrolysis. However, this residue appears to be absent from bacterial flagellins as well [1]. Other recurring similarities include the low amounts of proline, histidine, tyrosine, and methionine residues.…”

“…When compared with the amino acid compositions of other bacterial flagellins, there are many similarities with campylobacter. The most common feature between Campylobacter and other bacterial flagellins is the lack of cystine residues [1,2]. Of the medically important bacteria, this finding is also true for Salmonella [9,10] and Legionella [11].…”

“…and amino acid sequence [1,2]. Campylobacter jejuni flageUin has an apparent molecular weight of 62000 and appears to be homogeneous by molecular weight analysis.…”

On the Inheritance of Differentiated Traits

“…For example, genes on only one of the two X-chromosomes in female cells of eutherian mammals are expressed (Lyon, 1971(Lyon, , 1972. An analogous situation is that where only one of the two alleles that code for a flagellar protein is expressed in the bacterium Salmonella (Iino, 1969). I n conjunction with these examples, position effects (Lewis, 1950;McClintock, 1950) and particularly, variegated position effects in the fruit-fly, Drosophila (Baker, 1968), will be discussed.…”