Genetically predicted basal metabolic rate and venous thromboembolism risk: a Mendelian randomization study
Jian Huang,
Yubo Xie
Abstract:BackgroundBasal metabolic rate (BMR) is the minimum amount of energy needed by the body to carry out essential physiological functions. The goal of this study was to evaluate whether BMR causally influences venous thromboembolism (VTE) and its subtypes in European individuals.MethodsA two-sample Mendelian randomization (MR) was performed. Within a genome-wide association study (GWAS) involving 454,874 people, genetic variants were chosen as instrumental variables based on their significant associations (p &… Show more
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