Genetic variation of prevalent G1P[8] human rotaviruses in South Korea

Le, Van Phan; Chung, Yeon-Chang; Kim, Ki-Jeong; Chung, Sunyang; Lim, Inseok; Kim, Wonyong

doi:10.1002/jmv.21653

Cited by 34 publications

(33 citation statements)

References 58 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Rotavirus G1 genotype has been classified into 11 distinct lineages and 17 sublineages based on amino acids located at different positions [Phan et al, 2007a]. Studies carried out on this genotype have documented circulation of lineage IIA in Italy in the 1990s and lineages IA, ID, and III in Japan and Germany, IIC in Italy, III in Brazil, and IA in Bangladesh in the 2000s among children [Arista et al, 2006; Arau´jo et al, 2007; Phan et al, 2007a; Trinh et al, 2007; Dey et al, 2009a; Le et al, 2010; Pietsch et al, 2011]. The G1 strains recovered from adolescents and adults of the present study persistently showed sublineage specificity of IB and IC at both time points and that of IA only in the 1990s.…”

Section: Discussionmentioning

confidence: 99%

Diversity in the VP7 encoding genes of rotavirus strains isolated from adolescent and adult cases of acute gastroenteritis

Tatte

Chitambar

2012

Journal of Medical Virology

View full text Add to dashboard Cite

A study was conducted to examine the diversity in the VP7 genes of rotavirus strains circulating in adolescent and adult cases of acute gastroenteritis during two different time periods, 1993–1996 and 2004–2007. The multiplex RT‐PCR carried out on 131 rotavirus positive fecal specimens detected 65 (49.6%) single and 48 (36.6%) mixed infections of VP7 genotypes that included 43G1 (38.1%), 37G2 (32.7%), 8G3 (7.1%), 15G4 (13.3%), and 10G9 (8.8%) specificities. Sequencing and phylogenetic analysis of the VP7 gene amplicons revealed the presence of G1‐IA (4.7%), G1‐IB (69.8%), and G1‐IC (25.5%) lineages within the G1 strains, G2‐IIb1 (70.3%) and G2‐IIb2 (29.7%) lineages within G2 strains, G3‐3S1 (12.5%) and G3‐3S4 (87.5%) lineages within G3 strains, G4‐Ia (6.7%) and G4‐Ib (93.3%) lineages within G4 strains, and G9‐III lineage within G9 strains. The variability within VP7 genotypes was evident by 1.4–8.0% and 1.3–3.9% amino acid divergence respectively from the prototype strains and between the groups of strains at the two time points. This is the first report describing the phylogenetic analysis of VP7 genes of rotaviruses from adolescent and adult cases of acute gastroenteritis in India. Since adults infected with rotavirus could act as a source of infection and affect the epidemiology of rotaviruses in children, genetic analysis of the rotavirus strains circulating in adults is required. The intragenotypic diversity within VP7 genes demonstrated by the present study highlights the need for constant surveillance of rotavirus infections to understand better the evolution and transmission of group A rotaviruses in the community. J. Med. Virol. 84:1481–1488, 2012. © 2012 Wiley Periodicals, Inc.

show abstract

Section: Discussionmentioning

confidence: 99%

Diversity in the VP7 encoding genes of rotavirus strains isolated from adolescent and adult cases of acute gastroenteritis

Tatte

Chitambar

2012

Journal of Medical Virology

View full text Add to dashboard Cite

show abstract

“…In Korea, rotavirus is still the most common viral agent of acute diarrhea in young children. Although G1P[8] was the most prevalent strain until 1997 regardless of geographic area or season [6,9], the predominant G type strain has shifted to other genotypes including G4, G2 or G9 [10-13]. In the present study, we examined the diversity of the G and P types of human rotavirus strains isolated in South Korea during 2000 – 2004 periods.…”

Section: Introductionmentioning

confidence: 99%

Phylogenetic Analysis of the Rotavirus Genotypes Originated from Children < 5 Years of Age in 16 Cities in South Korea, between 2000 and 2004

Hong

Ahn

et al. 2012

Osong Public Health and Research Perspectives

View full text Add to dashboard Cite

ObjectivesThe purpose of this study was to examine the diversity of the G and P types of human rotavirus strains isolated in South Korea during 2000 to 2004.MethodsWe selected 38 Group A rotavirus isolates among 652 fecal samples, which were collected from infants and children < 5 years of age with acute gastroenteritis or diarrhea admitted in 8 hospitals representative of five provinces of South Korea between 2000 and 2004. Rotavirus P- and G-genotypes were determined by nucleotide sequencing and phylogenetic analysis was performed.ResultsOne G1P[4] consisted G1-Id-P[4]-V; one G1P[6] consisted G1-Id-P[6]-Ia; nine G1P[8] consisted G1-Ib-P[8]-Ia (n=3), G1-Ic-P[8]-Ia (n=1), and G1-Id-P[8]-Ia (n=5); 13 G2P[4] consisted G2-V-P[4]-V; two G3P[4] consisted G3-IIId-P[4]-V; five G3P[8] consisted G3-IIId-P[8]-Ia; four G4P[6] consisted G4-Ie-P[6]-Ia; two G4P[8] consisted G4-Ie-P[8]-II; one G9P[6] consisted G9-III-P[6]-Ia.ConclusionsA considerable amount of rotavirus genotypic diversity was detected in South Korea from 2000 to 2004. These findings are important to develop the effective vaccines and to undertake epidemiologic studies.

show abstract

“…Unlike other common strains (G1-G4), which are detected almost exclusively with P [8] or P [4], the G9 strains have been detected with variety of P types, including P [4], P [6], P [8], P [9], P [11], and P [19] [26]. The VP4 sequence analysis indicated that CAU05-202 belonged to the G9P [8] genotype.…”

mentioning

confidence: 99%

“…The presence of rotavirus strains in MA104 cells was determined by indirect immunofluorescence assay and polyacrylamide gel electrophoresis [19].…”

mentioning

confidence: 99%

Genomic characterization of a cell-culture-adapted Korean human G9P[8] rotavirus, CAU05-202

Shin

Than

et al. 2012

Arch Virol

Self Cite

View full text Add to dashboard Cite

The human rotavirus G9 strain is the fifth most common rotavirus worldwide. A human rotavirus G9P[8] strain CAU05-202 was isolated from a young child with diarrhea using a cell culture system, and its major gene sequences were determined. Phylogenetic analysis of the VP7 gene revealed that CAU05-202 clustered into genetic lineage III-d and was most closely related to G9 rotaviruses from Turkey (strain GUH13) and Sri Lanka (strain 05SLC056 and 05SLC057). VP4 and NSP4 gene analysis showed that CAU05-202 belongs to the P[8]-3 lineage and genotype B, respectively. In addition, CAU05-202 has a long RNA electropherotype, supported by VP6 gene analysis, which is clearly associated with subgroup II specificity. Analysis of the G9 rotavirus strain CAU05-202 provides information concerning the genetic relationships among global rotavirus G9 strains, suggesting that closely related G9 strains are persistent and widespread in Asian countries.

show abstract

Genetic variation of prevalent G1P[8] human rotaviruses in South Korea

Cited by 34 publications

References 58 publications

Diversity in the VP7 encoding genes of rotavirus strains isolated from adolescent and adult cases of acute gastroenteritis

Diversity in the VP7 encoding genes of rotavirus strains isolated from adolescent and adult cases of acute gastroenteritis

Phylogenetic Analysis of the Rotavirus Genotypes Originated from Children < 5 Years of Age in 16 Cities in South Korea, between 2000 and 2004

Genomic characterization of a cell-culture-adapted Korean human G9P[8] rotavirus, CAU05-202

Contact Info

Product

Resources

About