Genetic variation of<i>Aedes aegypti</i>populations from Ecuador

Cevallos,; Benítez, D.; Coloma, Joséfina; Carrazco, A; Wang, C; Holecheck, S; Quiroga, Cecilia Medina; Castillo, G.; Tillis, B; Ponce, Patricio

doi:10.1101/2019.12.17.875591

Cited by 3 publications

(1 citation statement)

References 50 publications

(75 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…West and East related African mitochondrial lineages have widely been reported throughout most of South American countries such as Peru, (20) Venezuela, (21) Argentina, (47) Bolivia, (23) Brazil, (22,48) and more recently in Ecuador. (49) In most of the cases, authors suggested multiple invasion sources for American populations occurred, which would explain differences in frequency for mitochondrial haplotypes observed throughout South America, (23,50,51) including Colombia. (18) However more recent research about historical demography and global genetic structure of Ae.…”

Section: Discussionmentioning

confidence: 99%

Population structure and ancestry prediction of Aedes aegypti (Diptera: Culicidae) supports a single African origin of Colombian populations

Monsalve

Triana-Chávez

Gómez-Palacio

2021

Mem. Inst. Oswaldo Cruz

View full text Add to dashboard Cite

BACKGROUND A previous phylogeographic study revealed two Aedes aegypti African-related mitochondrial lineages distributed in Colombian's cities with different eco-epidemiologic characteristics with regard to dengue virus (DENV). It has been proposed these lineages might indicate independent invasion sources. OBJECTIVES Assessing to Colombian population structure and to support evidence of its probable source origin.METHODS We analysed a total of 267 individuals from cities of Bello, Riohacha and Villavicencio, which 241 were related to the West and East African mitochondrial lineages (termed here as WAL and EAL, respectively). Eight polymorphic microsatellite loci were analysed aiming population structure.FINDINGS Results indicate substantial gene flow among distant and low-connected cities composing a panmictic population with incipient local differentiation of Ae. aegypti is placed in Colombia. Likewise, genetic evidence indicates no significant differences among individuals related to WAL and EAL is placed.MAIN CONCLUSIONS Minimal genetic differentiation in low-connected Ae. aegypti populations of Colombia, and lack concordance between mitochondrial and nuclear genealogies suggest that Colombian Ae. aegypti shared a common demographic history. Under this scenario, we suggest current Ae. aegypti population structure reflects a single origin instead of contemporary migration, which founding populations have a single source from a mitochondrial polymorphic African ancient.

show abstract

Section: Discussionmentioning

confidence: 99%

Population structure and ancestry prediction of Aedes aegypti (Diptera: Culicidae) supports a single African origin of Colombian populations

Monsalve

Triana-Chávez

Gómez-Palacio

2021

Mem. Inst. Oswaldo Cruz

View full text Add to dashboard Cite

show abstract

Molecular relationships of introducedAedes japonicus(Diptera: Culicidae) populations in British Columbia, Canada using mitochondrial DNA

Baharmand

Coatsworth

Peach

et al. 2020

Journal of Vector Ecology

View full text Add to dashboard Cite

Aedes japonicus japonicus (Theobald) is a relatively recent immigrant to the Pacific Northwest, having been collected in Washington State in 2001 and in British Columbia (BC) since 2014. We applied a molecular barcoding approach to determine the phylogenetic relationship of Ae. j. japonicus populations in BC with those from around the world. We sequenced a 617 base‐pair segment of the cytochrome c oxidase 1 gene and a 330 base‐pair region of the NADH dehydrogenase 4 gene to find genetic variation and characterize phylogenetic and haplotypic relationships based on nucleotide divergences. Our results revealed low genetic diversity in the BC samples, suggesting that these populations arose from the same introduction event. However, our approach lacked the granularity to identify the exact country of origin of the Ae. j. japonicus collected in BC. Future efforts should focus on detecting and preventing new Ae. j. japonicus introductions, recognizing that current molecular techniques are unable to pin‐point the precise source of an introduction.

show abstract

Two Haplotypes of Aedes aegypti Detected by ND4 Mitochondrial Marker in Three Regions of Ecuador

Ponce

Muñoz-Tobar

Carrazco-Montalvo

et al. 2021

Insects

View full text Add to dashboard Cite

Aedes aegypti, also known as the yellow fever mosquito, is the main vector of several arboviruses. In Ecuador, dengue and chikungunya are the most prevalent mosquito-borne diseases. Hence, there is a need to understand the population dynamics and genetic structure of the vector in tropical areas for a better approach towards effective vector control programs. This study aimed to assess the genetic diversity of Ae. aegypti, through the analyses of the mitochondrial gene ND4, using a combination of phylogenetic and population genetic structure from 17 sites in Ecuador. Results showed two haplotypes in the Ecuadorian populations of Ae. aegypti. Haplotype 1 was closely related to Ae. aegypti reported from America, Asia, and West Africa. Haplotype 2 was only related to samples from America. The sampled vectors from the diverse localities showed low nucleotide diversity (π = 0–0.01685) and genetic differentiation (FST = 0.152). AMOVA analyses indicated that most of the variation (85–91%) occurred within populations, suggesting that geographical barriers have little effect on the genetic structure of Ecuadorian populations of Ae. aegypti. These results agree with the one main population (K = 1) detected by Structure. Vector genetic identity may be a key factor in the planning of vector control strategies.

show abstract

Genetic variation ofAedes aegyptipopulations from Ecuador

Cited by 3 publications

References 50 publications

Population structure and ancestry prediction of Aedes aegypti (Diptera: Culicidae) supports a single African origin of Colombian populations

Population structure and ancestry prediction of Aedes aegypti (Diptera: Culicidae) supports a single African origin of Colombian populations

Molecular relationships of introducedAedes japonicus(Diptera: Culicidae) populations in British Columbia, Canada using mitochondrial DNA

Two Haplotypes of Aedes aegypti Detected by ND4 Mitochondrial Marker in Three Regions of Ecuador

Contact Info

Product

Resources

About